TFRC (transferrin receptor) - Rat Genome Database

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Gene: TFRC (transferrin receptor) Pan paniscus
Analyze
Symbol: TFRC
Name: transferrin receptor
RGD ID: 11756315
Description: ENCODES a protein that exhibits Hsp70 protein binding (ortholog); protein-folding chaperone binding (ortholog); transferrin receptor activity (ortholog); INVOLVED IN acute-phase response (ortholog); cellular response to leukemia inhibitory factor (ortholog); cellular response to xenobiotic stimulus (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; iron uptake pathway; ASSOCIATED WITH Acute-Phase Reaction (ortholog); Arenaviridae infectious disease (ortholog); autism spectrum disorder (ortholog); FOUND IN cell surface (ortholog); early endosome (ortholog); extracellular exosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transferrin receptor (p90, CD71); transferrin receptor protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22193,908,901 - 193,941,619 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13193,913,621 - 193,946,338 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,384,817 - 193,417,532 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,333,953 - 203,365,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,333,953 - 203,373,998 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TFRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22193,908,901 - 193,941,619 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13193,913,621 - 193,946,338 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,384,817 - 193,417,532 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,333,953 - 203,365,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,333,953 - 203,373,998 (-)Ensemblpanpan1.1panPan2
TFRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383196,049,284 - 196,082,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3196,012,511 - 196,082,153 (-)EnsemblGRCh38hg38GRCh38
GRCh373195,776,155 - 195,808,961 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,260,744 - 197,293,338 (-)NCBINCBI36Build 36hg18NCBI36
Build 343197,264,659 - 197,297,251NCBI
Celera3194,360,605 - 194,393,477 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3193,076,917 - 193,109,375 (-)NCBIHuRef
CHM1_13195,747,516 - 195,780,405 (-)NCBICHM1_1
T2T-CHM13v2.03198,738,962 - 198,802,440 (-)NCBIT2T-CHM13v2.0
Tfrc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,427,714 - 32,451,612 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,427,738 - 32,451,612 (+)EnsemblGRCm39 Ensembl
GRCm381632,608,896 - 32,632,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,608,920 - 32,632,794 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,608,982 - 32,632,880 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361632,528,768 - 32,552,537 (+)NCBIMGSCv36mm8
Celera1633,088,313 - 33,112,331 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1623.06NCBI
Tfrc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,668,478 - 81,690,318 (-)NCBIGRCr8
mRatBN7.21168,163,413 - 68,185,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,163,413 - 68,185,257 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,000,479 - 77,022,314 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,663,759 - 69,685,697 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,689,586 - 68,711,424 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,397,423 - 71,419,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,397,383 - 71,419,223 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,479,841 - 74,502,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,976,258 - 69,998,098 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11170,034,788 - 70,049,347 (-)NCBI
Celera1167,596,761 - 67,618,555 (-)NCBICelera
Cytogenetic Map11q22NCBI
Tfrc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,348,821 - 12,372,691 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,348,392 - 12,372,714 (-)NCBIChiLan1.0ChiLan1.0
TFRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,206,024 - 29,237,221 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,208,609 - 29,238,242 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3329,234,803 - 29,256,627 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03329,440,415 - 29,471,780 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3329,440,415 - 29,471,756 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13329,229,617 - 29,251,398 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03329,284,382 - 29,306,157 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03329,905,548 - 29,927,547 (-)NCBIUU_Cfam_GSD_1.0
Tfrc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602125,156,856 - 125,188,523 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936784696,713 - 728,543 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936784696,738 - 728,385 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13133,970,985 - 134,000,276 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113133,976,765 - 133,997,554 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213143,414,634 - 143,435,426 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11591,102,153 - 91,134,994 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1591,102,817 - 91,135,584 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604164,945,566 - 64,977,969 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfrc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,285,334 - 61,313,550 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473061,282,650 - 61,313,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000022728   ⟹   ENSPPAP00000004952
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,333,953 - 203,365,586 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000022754   ⟹   ENSPPAP00000004959
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,336,610 - 203,373,998 (-)Ensembl
RefSeq Acc Id: XM_003806407   ⟹   XP_003806455
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22193,908,901 - 193,941,461 (-)NCBI
NHGRI_mPanPan13193,913,621 - 193,946,193 (-)NCBI
Mhudiblu_PPA_v03193,384,817 - 193,417,454 (-)NCBI
PanPan1.13203,333,953 - 203,365,586 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034957961   ⟹   XP_034813852
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22193,908,901 - 193,941,619 (-)NCBI
NHGRI_mPanPan13193,913,621 - 193,946,338 (-)NCBI
Mhudiblu_PPA_v03193,384,817 - 193,417,532 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003806455 (Get FASTA)   NCBI Sequence Viewer  
  XP_034813852 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004952.1
  ENSPPAP00000004959.1
Reference Protein Sequences
RefSeq Acc Id: XP_003806455   ⟸   XM_003806407
- UniProtKB: A0A2R8ZIZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034813852   ⟸   XM_034957961
- UniProtKB: A0A2R8ZIZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000004952   ⟸   ENSPPAT00000022728
RefSeq Acc Id: ENSPPAP00000004959   ⟸   ENSPPAT00000022754
Protein Domains
PA   Peptidase M28   Transferrin receptor-like dimerisation


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000020743 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000022728.1 UniProtKB/TrEMBL
  ENSPPAT00000022754.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.930.40 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro PA_dom_sf UniProtKB/TrEMBL
  PA_domain UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
  Peptidase_M28B UniProtKB/TrEMBL
  TFR-like_dimer_dom UniProtKB/TrEMBL
  TFR-like_dimer_dom_sf UniProtKB/TrEMBL
  TfR1/2_PA UniProtKB/TrEMBL
KEGG Report pps:100986593 UniProtKB/TrEMBL
NCBI Gene TFRC ENTREZGENE
PANTHER PTHR10404 UniProtKB/TrEMBL
  PTHR10404:SF26 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
  PF02225 UniProtKB/TrEMBL
  TFR_dimer UniProtKB/TrEMBL
Superfamily-SCOP PA domain UniProtKB/TrEMBL
  SSF47672 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R8ZIZ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZJT8_PANPA UniProtKB/TrEMBL