THPO (thrombopoietin) - Rat Genome Database

Name: THPO
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: THPO (thrombopoietin) Pan paniscus

Analyze

Symbol:

THPO

Name:

thrombopoietin

RGD ID:

11734494

Description:

ENCODES a protein that exhibits cytokine activity (inferred); hormone activity (inferred); signaling receptor binding (inferred); INVOLVED IN myeloid cell differentiation (ortholog); positive regulation of hematopoietic stem cell proliferation (ortholog); positive regulation of megakaryocyte differentiation (ortholog); ASSOCIATED WITH 3-Methylcrotonyl-CoA carboxylase 1 deficiency (ortholog); aplastic anemia (ortholog); arteriosclerosis obliterans (ortholog); FOUND IN extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	THPO (thrombopoietin)	NCBI	Ortholog
Mus musculus (house mouse):	Thpo (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Thpo (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Thpo (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	THPO (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Thpo (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	THPO (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	THPO (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Thpo (thrombopoietin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,794 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	189,891,025 - 189,897,429 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	189,891,025 - 189,897,429 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-Methylcrotonyl-CoA carboxylase 1 deficiency (ISO)

aplastic anemia (ISO)

arteriosclerosis obliterans (ISO)

cardiomyopathy (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Congenital Amegakaryocytic Thrombocytopenia 2 (ISO)

congenital disorder of glycosylation Id (ISO)

Currarino syndrome (ISO)

essential thrombocythemia (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

liver cirrhosis (ISO)

pulmonary hypertension (ISO)

Stroke (ISO)

thrombocytopenia (ISO)

Thrombocytopenia 9 (ISO)

thrombocytosis (ISO)

toxic shock syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell population proliferation (IEA)

cell surface receptor signaling pathway via STAT (IEA)

megakaryocyte development (IEA)

megakaryocyte differentiation (IEA)

myeloid cell differentiation (ISO)

positive regulation of cell population proliferation (IEA)

positive regulation of ERK1 and ERK2 cascade (IEA)

positive regulation of hematopoietic stem cell proliferation (IEA,ISO)

positive regulation of MAPK cascade (IEA)

positive regulation of megakaryocyte differentiation (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

positive regulation of protein phosphorylation (ISO)

thrombopoietin-mediated signaling pathway (IEA)

Cellular Component

extracellular region (IEA)

Molecular Function

cytokine activity (IEA)

hormone activity (IEA)

signaling receptor binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

THPO
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,794 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	189,891,025 - 189,897,429 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	189,891,025 - 189,897,429 (-)	Ensembl	panpan1.1		panPan2

THPO
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	184,371,935 - 184,379,688 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	184,371,935 - 184,381,968 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	184,089,723 - 184,097,476 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	185,572,467 - 185,578,626 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	185,572,474 - 185,578,634	NCBI
Celera	3	182,530,743 - 182,536,902 (-)	NCBI		Celera
Cytogenetic Map	3	q27.1	NCBI
HuRef	3	181,496,308 - 181,502,467 (-)	NCBI		HuRef
CHM1_1	3	184,054,230 - 184,060,389 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	187,181,188 - 187,188,943 (-)	NCBI		T2T-CHM13v2.0

Thpo
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	20,543,204 - 20,553,261 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	20,543,204 - 20,553,261 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	20,724,454 - 20,734,511 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	20,724,454 - 20,734,511 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	20,724,527 - 20,734,584 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	20,637,997 - 20,648,054 (-)	NCBI		MGSCv36	mm8
Celera	16	21,289,807 - 21,299,861 (-)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI
cM Map	16	12.51	NCBI

Thpo
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2 Ensembl	11	80,182,820 - 80,188,167 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	11	82,845,676 - 82,853,439 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	82,848,853 - 82,852,425 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	11	83,868,655 - 83,873,910 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	85,925,385 - 85,932,532 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	82,412,552 - 82,417,807	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	11	79,022,653 - 79,027,908 (+)	NCBI		Celera
RH 3.4 Map	11		RGD
Cytogenetic Map	11	q23	NCBI

Thpo
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	23,123,637 - 23,129,198 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	23,120,828 - 23,128,894 (+)	NCBI	ChiLan1.0	ChiLan1.0

THPO
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	17,245,006 - 17,255,250 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	17,247,731 - 17,253,033 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	21,330,370 - 21,340,784 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	17,152,310 - 17,162,724 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	17,155,818 - 17,159,897 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	17,189,183 - 17,199,597 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	17,185,251 - 17,195,665 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	17,414,218 - 17,424,632 (-)	NCBI		UU_Cfam_GSD_1.0

Thpo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	119,414,449 - 119,423,408 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	5,509,111 - 5,515,103 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	5,508,669 - 5,515,984 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

THPO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	122,260,215 - 122,267,860 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	122,259,654 - 122,267,860 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	131,750,641 - 131,757,108 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

THPO
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	5,040,684 - 5,048,387 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666063	13,818,626 - 13,825,957 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Thpo
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	72,212,423 - 72,219,485 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	72,210,880 - 72,218,615 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003806597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008955435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008955436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024928195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034957839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034957840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063603011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000040350 ⟹ ENSPPAP00000017641

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	189,891,025 - 189,897,429 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000040356 ⟹ ENSPPAP00000017647

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	189,891,306 - 189,897,429 (-)	Ensembl

RefSeq Acc Id:

XM_003806597 ⟹ XP_003806645

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,790 (-)	NCBI
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI
PanPan1.1	3	189,891,025 - 189,897,429 (-)	NCBI

Sequence:

show sequence

CCAGCAACACAAATGTCCTGCCAGATTCCTCCTGGAAAAAAACTTCTGCTGCTGTCCCCCTCCA
GGTCCCAGGTTGCCCATGTCCAGGAAAAGATGGATGCCCCTATCCAAATCTTCTCCGTGGTGTG
TGTGGGTGGAGGAGTGGACCCTGGTCCAGGCAGGGGCTCCAGGGAAGAGAAGGCGTCACTTCCG
GGGGCCTTCACCAGTGTCTGGTGGCTCCCTTCTCTGATTGGGCAGAAGTGGCCCAGGCAGGCGT
ATGACCTGCTGCTGTGGAGGGGCTGTGCCCCACCGCCACATGTCTTCCTACCCATCTGCTCCCC
AGAGGGCTGCCTGCTGTGCACTTGGGTCCTGGAGCCCTTCTCCACCCGGATAGATTCCTCATCC
TTGGCCCGCCTTTGCCCCACCCTACTCTGCCCAGAAGTGCAAGAGCCCAAGCCGCCTCCATGGC
CCCAGGAAGGATTCAGGGGAGAGGCCCCAAACAGGGAGCCACGCCAGCCAGACACCCCGGCCAG
AATGGAGCTGACTGAATTGCTCCTCGTGGTCATGCTTCTCCTAACTGCAAGGCTAACGCTGTCC
AGCCCGGCTCCTCCTGCTTGTGACCTCCGAGTCCTCAGTAAACTGCTTCGTGACTCCCATGTCC
TTCACAGCAGGCTGAGCCAGTGCCCAGAGGTTCACCCTTTGCCTACACCTGTCCTGCTGCCTGC
TGTGGACTTTAGCTTGGGAGAATGGAAAACCCAGATGGAGGAGACCAAGGCACAGGACATTCTG
GGAGCAGTGACCCTTCTGCTGGAGGGAGTGATGGCAGCACGGGGACAACTGGGACCCACTTGCC
TCTCATCCCTCCTGGGGCAGCTTTCTGGACAGGTCCGTCTCCTCCTTGGGGCCCTGCAGAGCCT
CCTTGGAACCCAGCTTCCTCCACAGGGCAGGACCACAGCTCACAAGGATCCCAATGCCATCTTC
CTGAGCTTCCAACACCTGCTCCGAGGAAAGGTGCGTTTCCTGATGCTTGTAGGAGGGTCCACCC
TCTGCGTCAGGCGGGCCCCACCCACCACAGCTGTCCCCAGCAGAACCTCTCTAGTCCTCACACT
GAACGAGCTCCCAAACAGGACTTCTGGATTGTTGGAGACAAACTTCACTGCCTCAGCCAGAACT
ACTGGCTCTGGGCTTCTGAAGTGGCAGCAGGGATTCAGAGCCAAGATTCCTGGTCTGCTGAACC
AAACCTCCAGGTCCCTGGACCAAATCCCCGGATACCTGAACAGGATACACGAACTCTTGAATGG
AACTCGTGGACTCTTTCCTGGACCCTCACGCAGGACCCTAGGAGCCCCGGACATTTCCTCAGGA
ACATCAGACACAGGCTCCCTGCCACCCAACCTCCAGCCTGGATATTCTCCTTCCCCAACCCATC
CTCCTACTGGACAGTATACGCTCTTCCCTCTTCCACCCACCTTGCCCACCCCTGTGGTCCAGCT
CCACCGCCTGCTTCCTGACCCTTCTGCTCCAACGCCCACCCCTACCAGCCCTCTTCTAAACACA
TCCTACACCCACTCCCAGAATCTGTCTCAGGAAGGGTAAGGTTCTCAGACACTGCCGACATCAG
CATTGTCTCATGTACAGCTCCCTTCCCTGCAGGGCGCCCCTGGGAGACAACTGGACAAGATTTC
CTACTTTCTCCTGAAACCCAAAGCCCTGGTAAAAGGGATACACAGGACTGAAAAGGGAATCATT
TTTCACTGTACATTATAAACCTTCAGAAGCTATTTTTTTAAGCTATCAGCAATACTCATCAGAG
CAGCTAGCTCTTTGGTCTATTTTCTGCAGAAATTTGCAACTCACTGATTCTCTACATGCTCTTT
TTCTGTGATAATTCTGCAAAGGCCTGGGCTGGCCTGGCAGTTGAACAGAGGGAGAGACTAACCT
TGAGTCAGAAAACAGAGAAAGGGTAATTTCCTTTGCTTCAAATTCAAGGCCTTCCAACGCCCCC
ATCCCCTTTACTATCATTCTCAGTGGGACTCTGATCCCATATTCTTAACAGATCTTTACTCTTG
AGAAATGAATAAGCTGTCTCTCAGAAA

hide sequence

RefSeq Acc Id:

XM_008955435 ⟹ XP_008953683

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,793 (-)	NCBI
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI
PanPan1.1	3	189,891,306 - 189,897,429 (-)	NCBI

Sequence:

show sequence

CCAGCAACACAAATGTCCTGCCAGATTCCTCCTGGAAAAAAACTTCTGCTGCTGTCCCCCTCCA
GGTCCCAGGTTGCCCATGTCCAGGAAAAGATGGATGCCCCTATCCAAATCTTCTCCGTGGTGTG
TGTGGGTGGAGGAGTGGACCCTGGTCCAGGCAGGGGCTCCAGGGAAGAGAAGGCGTCACTTCCG
GGGGCCTTCACCAGTGTCTGGTGGCTCCCTTCTCTGATTGGGCAGAAGTGGCCCAGGCAGGCGT
ATGACCTGCTGCTGTGGAGGGGCTGTGCCCCACCGCCACATGTCTTCCTACCCATCTGCTCCCC
AGAGGGCTGCCTGCTGTGCACTTGGGTCCTGGAGCCCTTCTCCACCCGGATAGATTCCTCATCC
TTGGCCCGCCTTTGCCCCACCCTACTCTGCCCAGAAGTGCAAGAGCCCAAGCCGCCTCCATGGC
CCCAGGAAGGATTCAGGGGAGAGGCCCCAAACAGGGAGCCACGCCAGCCAGACACCCCGGCCAG
AATGGAGCTGACTGAATTGCTCCTCGTGGTCATGCTTCTCCTAACTGCAAGGCTAACGCTGTCC
AGCCCGGCTCCTCCTGCTTGTGACCTCCGAGTCCTCAGTAAACTGCTTCGTGACTCCCATGTCC
TTCACAGCAGGCTGAGCCAGTGCCCAGAGGTTCACCCTTTGCCTACACCTGTCCTGCTGCCTGC
TGTGGACTTTAGCTTGGGAGAATGGAAAACCCAGATGGAGGAGACCAAGGCACAGGACATTCTG
GGAGCAGTGACCCTTCTGCTGGAGGGAGTGATGGCAGCACGGGGACAACTGGGACCCACTTGCC
TCTCATCCCTCCTGGGGCAGCTTTCTGGACAGGTCCGTCTCCTCCTTGGGGCCCTGCAGAGCCT
CCTTGGAACCCAGGGCAGGACCACAGCTCACAAGGATCCCAATGCCATCTTCCTGAGCTTCCAA
CACCTGCTCCGAGGAAAGGTGCGTTTCCTGATGCTTGTAGGAGGGTCCACCCTCTGCGTCAGGC
GGGCCCCACCCACCACAGCTGTCCCCAGCAGAACCTCTCTAGTCCTCACACTGAACGAGCTCCC
AAACAGGACTTCTGGATTGTTGGAGACAAACTTCACTGCCTCAGCCAGAACTACTGGCTCTGGG
CTTCTGAAGTGGCAGCAGGGATTCAGAGCCAAGATTCCTGGTCTGCTGAACCAAACCTCCAGGT
CCCTGGACCAAATCCCCGGATACCTGAACAGGATACACGAACTCTTGAATGGAACTCGTGGACT
CTTTCCTGGACCCTCACGCAGGACCCTAGGAGCCCCGGACATTTCCTCAGGAACATCAGACACA
GGCTCCCTGCCACCCAACCTCCAGCCTGGATATTCTCCTTCCCCAACCCATCCTCCTACTGGAC
AGTATACGCTCTTCCCTCTTCCACCCACCTTGCCCACCCCTGTGGTCCAGCTCCACCGCCTGCT
TCCTGACCCTTCTGCTCCAACGCCCACCCCTACCAGCCCTCTTCTAAACACATCCTACACCCAC
TCCCAGAATCTGTCTCAGGAAGGGTAAGGTTCTCAGACACTGCCGACATCAGCATTGTCTCATG
TACAGCTCCCTTCCCTGCAGGGCGCCCCTGGGAGACAACTGGACAAGATTTCCTACTTTCTCCT
GAAACCCAAAGCCCTGGTAAAAGGGATACACAGGACTGAAAAGGGAATCATTTTTCACTGTACA
TTATAAACCTTCAGAAGCTATTTTTTTAAGCTATCAGCAATACTCATCAGAGCA

hide sequence

RefSeq Acc Id:

XM_008955436 ⟹ XP_008953684

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,791 (-)	NCBI
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI
PanPan1.1	3	189,891,306 - 189,897,429 (-)	NCBI

Sequence:

show sequence

CCAGCAACACAAATGTCCTGCCAGATTCCTCCTGGAAAAAAACTTCTGCTGCTGTCCCCCTCCA
GGTCCCAGGTTGCCCATGTCCAGGAAAAGATGGATGCCCCTATCCAAATCTTCTCCGTGGTGTG
TGTGGGTGGAGGAGTGGACCCTGGTCCAGGCAGGGGCTCCAGGGAAGAGAAGGCGTCACTTCCG
GGGGCCTTCACCAGTGTCTGGTGGCTCCCTTCTCTGATTGGGCAGAAGTGGCCCAGGCAGGCGT
ATGACCTGCTGCTGTGGAGGGGCTGTGCCCCACCGCCACATGTCTTCCTACCCATCTGCTCCCC
AGAGGGCTGCCTGCTGTGCACTTGGGTCCTGGAGCCCTTCTCCACCCGGATAGATTCCTCATCC
TTGGCCCGCCTTTGCCCCACCCTACTCTGCCCAGAAGTGCAAGAGCCCAAGCCGCCTCCATGGC
CCCAGGAAGGATTCAGGGGAGAGGCCCCAAACAGGGAGCCACGCCAGCCAGACACCCCGGCCAG
AATGGAGCTGACTGAATTGCTCCTCGTGGTCATGCTTCTCCTAACTGCAAGGCTAACGCTGTCC
AGCCCGGCTCCTCCTGCTTGTGACCTCCGAGTCCTCAGTAAACTGCTTCGTGACTCCCATGTCC
TTCACAGCAGGCTGAGCCAGTGCCCAGAGGTTCACCCTTTGCCTACACCTGTCCTGCTGCCTGC
TGTGGACTTTAGCTTGGGAGAATGGAAAACCCAGATGGAGGAGACCAAGGCACAGGACATTCTG
GGAGCAGTGACCCTTCTGCTGGAGGGAGTGATGGCAGCACGGGGACAACTGGGACCCACTTGCC
TCTCATCCCTCCTGGGGCAGCTTTCTGGACAGGTCCGTCTCCTCCTTGGGGCCCTGCAGAGCCT
CCTTGGAACCCAGCTTCCTCCACAGGGCAGGACCACAGCTCACAAGGATCCCAATGCCATCTTC
CTGAGCTTCCAACACCTGCTCCGAGGAAAGGACTTCTGGATTGTTGGAGACAAACTTCACTGCC
TCAGCCAGAACTACTGGCTCTGGGCTTCTGAAGTGGCAGCAGGGATTCAGAGCCAAGATTCCTG
GTCTGCTGAACCAAACCTCCAGGTCCCTGGACCAAATCCCCGGATACCTGAACAGGATACACGA
ACTCTTGAATGGAACTCGTGGACTCTTTCCTGGACCCTCACGCAGGACCCTAGGAGCCCCGGAC
ATTTCCTCAGGAACATCAGACACAGGCTCCCTGCCACCCAACCTCCAGCCTGGATATTCTCCTT
CCCCAACCCATCCTCCTACTGGACAGTATACGCTCTTCCCTCTTCCACCCACCTTGCCCACCCC
TGTGGTCCAGCTCCACCGCCTGCTTCCTGACCCTTCTGCTCCAACGCCCACCCCTACCAGCCCT
CTTCTAAACACATCCTACACCCACTCCCAGAATCTGTCTCAGGAAGGGTAAGGTTCTCAGACAC
TGCCGACATCAGCATTGTCTCATGTACAGCTCCCTTCCCTGCAGGGCGCCCCTGGGAGACAACT
GGACAAGATTTCCTACTTTCTCCTGAAACCCAAAGCCCTGGTAAAAGGGATACACAGGACTGAA
AAGGGAATCATTTTTCACTGTACATTATAAACCTTCAGAAGCTATTTTTTTAAGCTATCAGCAA
TACTCATCAGAGCA

hide sequence

RefSeq Acc Id:

XM_024928195 ⟹ XP_024783963

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,243,453 - 182,252,794 (-)	NCBI
NHGRI_mPanPan1	3	182,246,427 - 182,257,451 (-)	NCBI
Mhudiblu_PPA_v0	3	181,409,038 - 181,416,986 (-)	NCBI
PanPan1.1	3	189,891,306 - 189,897,429 (-)	NCBI

Sequence:

show sequence

CCAGCAACACAAATGTCCTGCCAGATTCCTCCTGGAAAAAAACTTCTGCTGCTGTCCCCCTCCA
GGTCCCAGGTTGCCCATGTCCAGGAAAAGATGGATGCCCCTATCCAAATCTTCTCCGTGGTGTG
TGTGGGTGGAGGAGTGGACCCTGGTCCAGGCAGGGGCTCCAGGGAAGAGAAGGCGTCACTTCCG
GGGGCCTTCACCAGTGTCTGGTGGCTCCCTTCTCTGATTGGGCAGAAGTGGCCCAGGCAGGCGT
ATGACCTGCTGCTGTGGAGGGGCTGTGCCCCACCGCCACATGTCTTCCTACCCATCTGCTCCCC
AGAGGGCTGCCTGCTGTGCACTTGGGTCCTGGAGCCCTTCTCCACCCGGATAGATTCCTCATCC
TTGGCCCGCCTTTGCCCCACCCTACTCTGCCCAGAAGTGCAAGAGCCCAAGCCGCCTCCATGGC
CCCAGGAAGGATTCAGGGGAGAGGCCCCAAACAGGGAGCCACGCCAGCCAGACACCCCGGCCAG
AATGGAGCTGACTGAATTGCTCCTCGTGGTCATGCTTCTCCTAACTGCAAGGCTAACGCTGTCC
AGCCCGGCTCCTCCTGCTTGTGACCTCCGAGTCCTCAGTAAACTGCTTCGTGACTCCCATGTCC
TTCACAGCAGGCTGAGCCAGTGCCCAGAGGTTCACCCTTTGCCTACACCTGTCCTGCTGCCTGC
TGTGGACTTTAGCTTGGGAGAATGGAAAACCCAGATGGAGGAGACCAAGGCACAGGACATTCTG
GGAGCAGTGACCCTTCTGCTGGAGGGAGTGATGGCAGCACGGGGACAACTGGGACCCACTTGCC
TCTCATCCCTCCTGGGGCAGCTTTCTGGACAGGTCCGTCTCCTCCTTGGGGCCCTGCAGAGCCT
CCTTGGAACCCAGGGCAGGACCACAGCTCACAAGGATCCCAATGCCATCTTCCTGAGCTTCCAA
CACCTGCTCCGAGGAAAGGACTTCTGGATTGTTGGAGACAAACTTCACTGCCTCAGCCAGAACT
ACTGGCTCTGGGCTTCTGAAGTGGCAGCAGGGATTCAGAGCCAAGATTCCTGGTCTGCTGAACC
AAACCTCCAGGTCCCTGGACCAAATCCCCGGATACCTGAACAGGATACACGAACTCTTGAATGG
AACTCGTGGACTCTTTCCTGGACCCTCACGCAGGACCCTAGGAGCCCCGGACATTTCCTCAGGA
ACATCAGACACAGGCTCCCTGCCACCCAACCTCCAGCCTGGATATTCTCCTTCCCCAACCCATC
CTCCTACTGGACAGTATACGCTCTTCCCTCTTCCACCCACCTTGCCCACCCCTGTGGTCCAGCT
CCACCGCCTGCTTCCTGACCCTTCTGCTCCAACGCCCACCCCTACCAGCCCTCTTCTAAACACA
TCCTACACCCACTCCCAGAATCTGTCTCAGGAAGGGTAAGGTTCTCAGACACTGCCGACATCAG
CATTGTCTCATGTACAGCTCCCTTCCCTGCAGGGCGCCCCTGGGAGACAACTGGACAAGATTTC
CTACTTTCTCCTGAAACCCAAAGCCCTGGTAAAAGGGATACACAGGACTGAAAAGGGAATCATT
TTTCACTGTACATTATAAACCTTCAGAAGCTATTTTTTTAAGCTATCAGCAATACTCATCAGAG
CA

hide sequence

RefSeq Acc Id:

XM_063603011 ⟹ XP_063459081

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,243,453 - 182,250,175 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003806645	(Get FASTA)	NCBI Sequence Viewer
	XP_008953683	(Get FASTA)	NCBI Sequence Viewer
	XP_008953684	(Get FASTA)	NCBI Sequence Viewer
	XP_024783963	(Get FASTA)	NCBI Sequence Viewer
	XP_063459081	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000017641.1
	ENSPPAP00000017647.1

RefSeq Acc Id:

XP_003806645 ⟸ XM_003806597

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSCQIPPGKKLLLLSPSRSQVAHVQEKMDAPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFT
SVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSSLARL
CPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAP
PACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVT
LLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQ
HLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSG
LLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDT
GSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHRLLPDPSAPTPTPTSPLLNTSYTH
SQNLSQEG

hide sequence

RefSeq Acc Id:

XP_008953683 ⟸ XM_008955435

- Peptide Label:

isoform X2

- Sequence:

show sequence

MSCQIPPGKKLLLLSPSRSQVAHVQEKMDAPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFT
SVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSSLARL
CPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAP
PACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVT
LLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQGRTTAHKDPNAIFLSFQHLLR
GKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKW
QQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLP
PNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHRLLPDPSAPTPTPTSPLLNTSYTHSQNL
SQEG

hide sequence

RefSeq Acc Id:

XP_008953684 ⟸ XM_008955436

- Peptide Label:

isoform X3

- Sequence:

show sequence

MSCQIPPGKKLLLLSPSRSQVAHVQEKMDAPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFT
SVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSSLARL
CPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAP
PACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVT
LLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQ
HLLRGKDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEW
NSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPA
PPPAS

hide sequence

RefSeq Acc Id:

XP_024783963 ⟸ XM_024928195

- Peptide Label:

isoform X4

- Sequence:

show sequence

MSCQIPPGKKLLLLSPSRSQVAHVQEKMDAPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFT
SVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSSLARL
CPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAP
PACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVT
LLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQGRTTAHKDPNAIFLSFQHLLR
GKDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWT
LSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPA
S

hide sequence

RefSeq Acc Id:

ENSPPAP00000017647 ⟸ ENSPPAT00000040356

RefSeq Acc Id:

ENSPPAP00000017641 ⟸ ENSPPAT00000040350

RefSeq Acc Id:	XP_063459081 ⟸ XM_063603011
- Peptide Label:	isoform X5

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000031907	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000040350.1	UniProtKB/TrEMBL
	ENSPPAT00000040356.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.10	UniProtKB/TrEMBL
InterPro	4_helix_cytokine-like_core	UniProtKB/TrEMBL
	EPO/TPO_CS	UniProtKB/TrEMBL
	EPO_TPO	UniProtKB/TrEMBL
	Thrombopoietin	UniProtKB/TrEMBL
NCBI Gene	THPO	ENTREZGENE
PANTHER	PTHR10560	UniProtKB/TrEMBL
	THROMBOPOIETIN	UniProtKB/TrEMBL
Pfam	EPO_TPO	UniProtKB/TrEMBL
PRINTS	THROMBOPTN	UniProtKB/TrEMBL
PROSITE	EPO_TPO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47266	UniProtKB/TrEMBL
UniProt	A0A2R9AJU1_PANPA	UniProtKB/TrEMBL
	A0A2R9AJU9_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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