KCNN1 (potassium calcium-activated channel subfamily N member 1) - Rat Genome Database

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Gene: KCNN1 (potassium calcium-activated channel subfamily N member 1) Pan paniscus
Analyze
Symbol: KCNN1
Name: potassium calcium-activated channel subfamily N member 1
RGD ID: 11732739
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transport (inferred); potassium ion transmembrane transport (inferred); potassium ion transport (inferred); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH genetic disease (ortholog); Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; small conductance calcium-activated potassium channel protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,813,690 - 22,859,843 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,820,499 - 21,868,525 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,430,795 - 17,478,981 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,405,077 - 18,455,686 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,422,231 - 18,458,630 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,813,690 - 22,859,843 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,820,499 - 21,868,525 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,430,795 - 17,478,981 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,405,077 - 18,455,686 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,422,231 - 18,458,630 (+)Ensemblpanpan1.1panPan2
KCNN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,951,290 - 18,000,085 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,951,293 - 18,000,085 (+)EnsemblGRCh38hg38GRCh38
GRCh371918,062,099 - 18,110,894 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,923,111 - 17,970,930 (+)NCBINCBI36Build 36hg18NCBI36
Build 341917,923,110 - 17,970,930NCBI
Celera1917,963,835 - 18,011,634 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,627,350 - 17,675,149 (+)NCBIHuRef
CHM1_11918,061,819 - 18,109,567 (+)NCBICHM1_1
T2T-CHM13v2.01918,085,382 - 18,134,163 (+)NCBIT2T-CHM13v2.0
Kcnn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,295,802 - 71,318,335 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,294,693 - 71,315,902 (-)EnsemblGRCm39 Ensembl
GRCm38870,843,158 - 70,865,691 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,842,049 - 70,863,258 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,365,948 - 73,380,907 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,772,147 - 73,784,574 (-)NCBIMGSCv36mm8
Celera873,403,345 - 73,418,311 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.27NCBI
Kcnn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,608,782 - 18,632,571 (+)NCBIGRCr8
mRatBN7.21618,574,858 - 18,598,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,585,992 - 18,597,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,628,268 - 18,639,511 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,760,948 - 19,772,191 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,681,212 - 18,692,455 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,325,270 - 20,349,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,336,638 - 20,348,804 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,194,340 - 20,206,261 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11619,093,437 - 19,103,818 (+)NCBI
Celera1618,778,700 - 18,789,456 (+)NCBICelera
Cytogenetic Map16p14NCBI
Kcnn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,322,551 - 3,344,346 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,323,188 - 3,344,321 (-)NCBIChiLan1.0ChiLan1.0
KCNN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,939,619 - 44,971,923 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,939,603 - 44,969,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,852,263 - 44,883,423 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,424,541 - 45,455,928 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,424,773 - 45,454,118 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,661,785 - 44,685,096 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,071,928 - 45,103,070 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,347,879 - 45,379,261 (-)NCBIUU_Cfam_GSD_1.0
Kcnn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,558,492 - 203,574,294 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365963,107,925 - 3,123,942 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365963,107,631 - 3,123,433 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,780,013 - 59,817,059 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,780,010 - 59,814,815 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,348,738 - 59,385,538 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,440,908 - 16,470,613 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,448,038 - 16,472,319 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,908,764 - 2,956,592 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,442,553 - 1,451,205 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,438,592 - 1,451,980 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014342573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014342576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014342577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014342578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055104428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055104429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055104430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008622205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008622206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000031585   ⟹   ENSPPAP00000008946
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,422,231 - 18,455,686 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000031594   ⟹   ENSPPAP00000008954
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,429,157 - 18,458,630 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000031600   ⟹   ENSPPAP00000008960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,429,157 - 18,456,550 (+)Ensembl
RefSeq Acc Id: XM_014342578   ⟹   XP_014198064
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,829,788 - 22,859,843 (+)NCBI
NHGRI_mPanPan11921,836,606 - 21,868,525 (+)NCBI
Mhudiblu_PPA_v01917,446,960 - 17,478,981 (+)NCBI
PanPan1.11918,422,231 - 18,455,686 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055104428   ⟹   XP_054960403
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,829,821 - 22,859,843 (+)NCBI
NHGRI_mPanPan11921,836,659 - 21,868,525 (+)NCBI
RefSeq Acc Id: XM_055104429   ⟹   XP_054960404
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,814,858 - 22,859,843 (+)NCBI
NHGRI_mPanPan11921,821,676 - 21,868,525 (+)NCBI
RefSeq Acc Id: XM_055104430   ⟹   XP_054960405
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,813,690 - 22,859,843 (+)NCBI
NHGRI_mPanPan11921,820,499 - 21,868,525 (+)NCBI
RefSeq Acc Id: XR_008622205
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,829,823 - 22,859,008 (+)NCBI
NHGRI_mPanPan11921,836,659 - 21,867,690 (+)NCBI
RefSeq Acc Id: XR_008622206
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,829,822 - 22,858,971 (+)NCBI
NHGRI_mPanPan11921,836,659 - 21,867,653 (+)NCBI
Protein Sequences
Protein RefSeqs XP_014198064 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960403 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960404 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960405 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008946.1
  ENSPPAP00000008954.1
  ENSPPAP00000008960.1
Reference Protein Sequences
RefSeq Acc Id: XP_014198064   ⟸   XM_014342578
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZWL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000008954   ⟸   ENSPPAT00000031594
RefSeq Acc Id: ENSPPAP00000008946   ⟸   ENSPPAT00000031585
RefSeq Acc Id: ENSPPAP00000008960   ⟸   ENSPPAT00000031600
RefSeq Acc Id: XP_054960405   ⟸   XM_055104430
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZWL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960404   ⟸   XM_055104429
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZWL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960403   ⟸   XM_055104428
- Peptide Label: isoform X1
Protein Domains
Calmodulin-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027691 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031585.1 UniProtKB/TrEMBL
  ENSPPAT00000031594.1 UniProtKB/TrEMBL
  ENSPPAT00000031600.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
InterPro CaM-bd_dom UniProtKB/TrEMBL
  CaM-bd_dom_sf UniProtKB/TrEMBL
  K_chnl_Ca-activ_SK UniProtKB/TrEMBL
  K_chnl_dom UniProtKB/TrEMBL
NCBI Gene KCNN1 ENTREZGENE
PANTHER PTHR10153 UniProtKB/TrEMBL
  SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 UniProtKB/TrEMBL
Pfam CaMBD UniProtKB/TrEMBL
  Ion_trans_2 UniProtKB/TrEMBL
  SK_channel UniProtKB/TrEMBL
PRINTS SKCHANNEL UniProtKB/TrEMBL
SMART CaMBD UniProtKB/TrEMBL
Superfamily-SCOP SSF81327 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A2R8ZVG7_PANPA UniProtKB/TrEMBL
  A0A2R8ZVH5_PANPA UniProtKB/TrEMBL
  A0A2R8ZWL8 ENTREZGENE, UniProtKB/TrEMBL