PSMB2 (proteasome 20S subunit beta 2) - Rat Genome Database

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Gene: PSMB2 (proteasome 20S subunit beta 2) Pan paniscus
Analyze
Symbol: PSMB2
Name: proteasome 20S subunit beta 2
RGD ID: 11716995
Description: INVOLVED IN response to organic cyclic compound (ortholog); response to organonitrogen compound (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proteasome (prosome, macropain) subunit, beta type, 2; proteasome subunit beta 2; proteasome subunit beta type-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,200,350 - 191,243,105 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11190,322,175 - 190,364,242 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0134,869,524 - 34,911,852 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1136,046,963 - 36,090,294 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl136,046,963 - 36,090,294 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PSMB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,200,350 - 191,243,105 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11190,322,175 - 190,364,242 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0134,869,524 - 34,911,852 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1136,046,963 - 36,090,294 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl136,046,963 - 36,090,294 (-)Ensemblpanpan1.1panPan2
PSMB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38135,599,541 - 35,641,526 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl135,599,541 - 35,641,526 (-)EnsemblGRCh38hg38GRCh38
GRCh37136,065,142 - 36,107,127 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36135,841,326 - 35,879,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 34135,737,832 - 35,776,236NCBI
Celera134,343,105 - 34,381,638 (-)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef134,183,411 - 34,225,581 (-)NCBIHuRef
CHM1_1136,181,300 - 36,223,606 (-)NCBICHM1_1
T2T-CHM13v2.0135,462,557 - 35,504,550 (-)NCBIT2T-CHM13v2.0
Psmb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394126,571,460 - 126,603,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4126,571,423 - 126,603,507 (+)EnsemblGRCm39 Ensembl
GRCm384126,677,637 - 126,709,715 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4126,677,630 - 126,709,714 (+)EnsemblGRCm38mm10GRCm38
MGSCv374126,354,887 - 126,386,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364126,179,970 - 126,212,010 (+)NCBIMGSCv36mm8
Celera4125,014,138 - 125,049,448 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map460.9NCBI
Psmb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85144,255,058 - 144,287,200 (+)NCBIGRCr8
mRatBN7.25138,970,564 - 139,002,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5138,970,533 - 139,021,137 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5141,666,617 - 141,698,783 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05143,436,619 - 143,468,759 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05143,437,414 - 143,469,574 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05144,702,004 - 144,734,220 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5144,701,949 - 144,734,257 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05148,472,394 - 148,504,751 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45146,089,234 - 146,121,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15146,099,272 - 146,132,017 (+)NCBI
Celera5137,466,198 - 137,498,177 (+)NCBICelera
Cytogenetic Map5q36NCBI
Psmb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545213,685,548 - 13,725,360 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545213,688,218 - 13,725,318 (-)NCBIChiLan1.0ChiLan1.0
PSMB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1156,511,281 - 6,544,859 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl156,511,325 - 6,544,857 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha156,753,572 - 6,787,064 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0156,647,326 - 6,680,810 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl156,647,371 - 6,680,808 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1156,499,532 - 6,532,817 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0156,568,457 - 6,601,946 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,582,711 - 6,616,186 (+)NCBIUU_Cfam_GSD_1.0
Psmb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505852,326,935 - 52,358,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647418,151,490 - 18,183,440 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647418,151,717 - 18,183,384 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl691,783,058 - 91,829,908 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1691,792,055 - 91,829,942 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PSMB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12097,232,632 - 97,270,608 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2097,232,632 - 97,270,973 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603319,448,515 - 19,486,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476418,650,839 - 18,688,035 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476418,653,691 - 18,688,037 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003812572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000064839   ⟹   ENSPPAP00000041911
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl136,046,963 - 36,090,294 (-)Ensembl
RefSeq Acc Id: XM_003812572   ⟹   XP_003812620
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21191,200,350 - 191,243,105 (+)NCBI
NHGRI_mPanPan11190,322,175 - 190,364,242 (+)NCBI
Mhudiblu_PPA_v0134,869,524 - 34,911,852 (-)NCBI
PanPan1.1136,046,963 - 36,090,294 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003812620 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041911
  ENSPPAP00000041911.1
Reference Protein Sequences
RefSeq Acc Id: XP_003812620   ⟸   XM_003812572
- UniProtKB: A0A2R9CIW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000041911   ⟸   ENSPPAT00000064839


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043554 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064839.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Proteasome_beta2 UniProtKB/TrEMBL
  Proteasome_bsu_CS UniProtKB/TrEMBL
  Proteasome_sua/b UniProtKB/TrEMBL
  Proteasome_suB-type UniProtKB/TrEMBL
KEGG Report pps:100995258 UniProtKB/TrEMBL
NCBI Gene PSMB2 ENTREZGENE
PANTHER PROTEASOME SUBUNIT ALPHA/BETA UniProtKB/TrEMBL
  PTHR11599:SF6 UniProtKB/TrEMBL
Pfam Proteasome UniProtKB/TrEMBL
PROSITE PROTEASOME_BETA_1 UniProtKB/TrEMBL
  PROTEASOME_BETA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A2R9CIW3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-03 PSMB2  proteasome 20S subunit beta 2  PSMB2  proteasome subunit beta 2  Symbol and/or name change 5135510 APPROVED