SV2A (synaptic vesicle glycoprotein 2A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SV2A (synaptic vesicle glycoprotein 2A) Pan paniscus
Analyze
Symbol: SV2A
Name: synaptic vesicle glycoprotein 2A
RGD ID: 11707995
Description: ENCODES a protein that exhibits protein kinase binding (inferred); transmembrane transporter activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); regulation of gamma-aminobutyric acid secretion (ortholog); ASSOCIATED WITH Experimental Seizures (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,921,893 - 99,936,495 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,676,850 - 99,691,458 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,247,429 - 125,262,041 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11128,904,140 - 128,918,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1128,904,151 - 128,918,829 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SV2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,921,893 - 99,936,495 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,676,850 - 99,691,458 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,247,429 - 125,262,041 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11128,904,140 - 128,918,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1128,904,151 - 128,918,829 (-)Ensemblpanpan1.1panPan2
SV2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381149,903,318 - 149,917,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1149,903,318 - 149,917,844 (-)EnsemblGRCh38hg38GRCh38
GRCh371149,874,870 - 149,889,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,141,859 - 148,156,054 (-)NCBINCBI36Build 36hg18NCBI36
Celera1122,990,840 - 123,005,404 (-)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,255,354 - 121,269,918 (-)NCBIHuRef
CHM1_11151,271,444 - 151,286,008 (-)NCBICHM1_1
T2T-CHM13v2.01149,027,459 - 149,041,985 (-)NCBIT2T-CHM13v2.0
Sv2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39396,088,543 - 96,102,499 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl396,088,467 - 96,102,837 (+)EnsemblGRCm39 Ensembl
GRCm38396,181,227 - 96,195,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl396,181,151 - 96,195,521 (+)EnsemblGRCm38mm10GRCm38
MGSCv37395,985,150 - 95,999,106 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36396,266,632 - 96,280,588 (+)NCBIMGSCv36mm8
Celera397,620,657 - 97,631,186 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.65NCBI
Sv2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82186,430,363 - 186,446,161 (+)NCBIGRCr8
mRatBN7.22183,741,489 - 183,757,290 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,741,547 - 183,756,927 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,405,136 - 191,420,924 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02189,209,456 - 189,225,293 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02184,037,670 - 184,053,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02198,321,100 - 198,336,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2198,321,142 - 198,336,913 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,808,165 - 217,823,872 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,989,187 - 191,000,859 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12190,948,188 - 190,963,566 (+)NCBI
Celera2176,272,713 - 176,284,621 (+)NCBICelera
Cytogenetic Map2q34NCBI
Sv2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955413834,743 - 851,023 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955413834,743 - 849,176 (+)NCBIChiLan1.0ChiLan1.0
SV2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,185,715 - 59,195,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,187,244 - 59,195,888 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,633,794 - 58,647,878 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,182,727 - 60,196,808 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,182,738 - 60,196,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,032,197 - 59,046,284 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,115,941 - 59,130,018 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01759,843,004 - 59,857,105 (-)NCBIUU_Cfam_GSD_1.0
Sv2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,213,447 - 21,227,353 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936580243,792 - 257,760 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936580243,829 - 257,708 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SV2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl499,138,342 - 99,153,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1499,138,319 - 99,153,153 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24108,567,034 - 108,581,274 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SV2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,389,665 - 13,404,056 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sv2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477217,681,299 - 17,696,884 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477217,684,061 - 17,698,728 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003817323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000033185   ⟹   ENSPPAP00000010533
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,904,151 - 128,918,829 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000033199   ⟹   ENSPPAP00000010547
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,904,545 - 128,914,664 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000033201   ⟹   ENSPPAP00000010549
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,905,836 - 128,914,664 (-)Ensembl
RefSeq Acc Id: XM_003817323   ⟹   XP_003817371
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,921,893 - 99,936,495 (+)NCBI
NHGRI_mPanPan1199,676,850 - 99,691,458 (+)NCBI
Mhudiblu_PPA_v01125,247,429 - 125,262,041 (-)NCBI
PanPan1.11128,904,140 - 128,918,829 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003817371 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000010533
  ENSPPAP00000010533.1
  ENSPPAP00000010547.1
  ENSPPAP00000010549.1
Reference Protein Sequences
RefSeq Acc Id: XP_003817371   ⟸   XM_003817323
- UniProtKB: A0A2R9A117 (UniProtKB/TrEMBL),   A0A2R9A486 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000010533   ⟸   ENSPPAT00000033185
RefSeq Acc Id: ENSPPAP00000010547   ⟸   ENSPPAT00000033199
RefSeq Acc Id: ENSPPAP00000010549   ⟸   ENSPPAT00000033201
Protein Domains
Major facilitator superfamily (MFS) profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028470 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033185.1 UniProtKB/TrEMBL
  ENSPPAT00000033199.1 UniProtKB/TrEMBL
  ENSPPAT00000033201.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
  E3 ubiquitin-protein ligase SopA UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/TrEMBL
  SV2 UniProtKB/TrEMBL
KEGG Report pps:100985099 UniProtKB/TrEMBL
NCBI Gene SV2A ENTREZGENE
PANTHER SYNAPTIC VESICLE GLYCOPROTEIN 2 UniProtKB/TrEMBL
  SYNAPTIC VESICLE GLYCOPROTEIN 2A UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
  Sugar_tr UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
  SUGAR_TRANSPORT_2 UniProtKB/TrEMBL
Superfamily-SCOP Pentapeptide repeat-like UniProtKB/TrEMBL
  SSF103473 UniProtKB/TrEMBL
UniProt A0A2R8ZZY0_PANPA UniProtKB/TrEMBL
  A0A2R9A117 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A486 ENTREZGENE, UniProtKB/TrEMBL