C10h5orf58 (similar to human chromosome 5 open reading frame 58) - Rat Genome Database

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Gene: C10h5orf58 (similar to human chromosome 5 open reading frame 58) Rattus norvegicus
Analyze
Symbol: C10h5orf58
Name: similar to human chromosome 5 open reading frame 58 (Ensembl:chromosome 10 open reading frame, human C5orf58)
RGD ID: 11411272
Description: Orthologous to human C5orf58 (chromosome 5 open reading frame 58); INTERACTS WITH arsenous acid (ortholog); CU-O LINKAGE (ortholog); diarsenic trioxide (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome 10 open reading frame, human C5orf58; putative uncharacterized protein C5orf58 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81019,195,306 - 19,203,013 (-)NCBIGRCr8
mRatBN7.21018,690,958 - 18,697,224 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1018,688,847 - 18,697,220 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01019,043,374 - 19,052,918 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera1018,322,412 - 18,331,962 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
C10h5orf58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81019,195,306 - 19,203,013 (-)NCBIGRCr8
mRatBN7.21018,690,958 - 18,697,224 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1018,688,847 - 18,697,220 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01019,043,374 - 19,052,918 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera1018,322,412 - 18,331,962 (-)NCBICelera
Cytogenetic Map10q12NCBI
C5orf58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385170,232,985 - 170,252,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5170,229,104 - 170,252,575 (+)EnsemblGRCh38hg38GRCh38
GRCh375169,659,989 - 169,679,574 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365169,592,528 - 169,605,813 (+)NCBINCBI36Build 36hg18NCBI36
Celera5165,691,873 - 165,705,161 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5164,758,426 - 164,771,711 (+)NCBIHuRef
CHM1_15169,092,406 - 169,105,691 (+)NCBICHM1_1
T2T-CHM13v2.05170,771,839 - 170,791,430 (+)NCBIT2T-CHM13v2.0
4930469K13Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,923,961 - 34,048,554 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,923,961 - 34,048,554 (-)EnsemblGRCm39 Ensembl
GRCm381133,973,961 - 34,098,554 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,973,961 - 34,098,554 (-)EnsemblGRCm38mm10GRCm38
Celera1136,476,885 - 36,511,757 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.33NCBI
LOC102016025
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540823,186,712 - 23,197,682 (+)NCBIChiLan1.0ChiLan1.0
C4H5orf58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24165,390,079 - 165,403,420 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15163,529,622 - 163,540,760 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05165,592,644 - 165,605,937 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15172,356,037 - 172,363,327 (+)NCBIpanpan1.1PanPan1.1panPan2
C4H5orf58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1441,656,638 - 41,665,051 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha441,608,640 - 41,617,091 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0442,032,461 - 42,040,931 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1441,849,694 - 41,858,143 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0442,036,532 - 42,045,007 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0442,547,230 - 42,555,686 (-)NCBIUU_Cfam_GSD_1.0
CUNH5orf58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721395,844,194 - 95,854,984 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366094,570,785 - 4,572,903 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C16H5orf58
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11653,740,219 - 53,747,279 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21658,084,258 - 58,097,742 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH5orf58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12372,444,166 - 72,448,027 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660346,214,154 - 6,222,652 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH5orf58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473319,721,377 - 19,728,144 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C10h5orf58
46 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101724551319388279Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000110174   ⟹   ENSRNOP00000077696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1018,688,847 - 18,697,220 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116466   ⟹   ENSRNOP00000080535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1018,691,119 - 18,697,220 (-)Ensembl
RefSeq Acc Id: XM_017597835   ⟹   XP_017453324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81019,195,306 - 19,203,013 (-)NCBI
mRatBN7.21018,690,958 - 18,697,224 (-)NCBI
Rnor_6.01019,043,374 - 19,052,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597836   ⟹   XP_017453325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81019,195,306 - 19,203,013 (-)NCBI
mRatBN7.21018,690,962 - 18,697,224 (-)NCBI
Rnor_6.01019,043,374 - 19,052,918 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017453324 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453325 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000077696.1
  ENSRNOP00000080535
  ENSRNOP00000080535.1
Reference Protein Sequences
RefSeq Acc Id: XP_017453325   ⟸   XM_017597836
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZKC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453324   ⟸   XM_017597835
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPU1 (UniProtKB/TrEMBL),   A0A8I5ZKC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000077696   ⟸   ENSRNOT00000110174
RefSeq Acc Id: ENSRNOP00000080535   ⟸   ENSRNOT00000116466

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:11411272 AgrOrtholog
BioCyc Gene G2FUF-25589 BioCyc
Ensembl Genes ENSRNOG00000068310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000110174.1 UniProtKB/TrEMBL
  ENSRNOT00000116466.1 UniProtKB/TrEMBL
KEGG Report rno:108352200 UniProtKB/TrEMBL
NCBI Gene C10H5orf58 ENTREZGENE
PhenoGen C10h5orf58 PhenoGen
RatGTEx ENSRNOG00000068310 RatGTEx
UniProt A0A8I5ZKC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPU1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-01-09 C10h5orf58  similar to human chromosome 5 open reading frame 58  C10H5orf58  chromosome 10 open reading frame, human C5orf58  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-02 C10H5orf58  chromosome 10 open reading frame, human C5orf58  C10H5orf58  chromosome 10 open reading frame, human C5orf58  Data merged from RGD:149736537 737654 PROVISIONAL
2021-08-09 C10H5orf58  chromosome 10 open reading frame, human C5orf58      Symbol and Name status set to provisional 45752 PROVISIONAL
2016-08-02 C10H5orf58  chromosome 10 open reading frame, human C5orf58      Symbol and Name status set to provisional 70820 PROVISIONAL