Ptpra (protein tyrosine phosphatase receptor type A) - Rat Genome Database

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Pathways
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Gene: Ptpra (protein tyrosine phosphatase receptor type A) Mus musculus
Analyze
Symbol: Ptpra
Name: protein tyrosine phosphatase receptor type A
RGD ID: 11194
MGI Page MGI
Description: Enables protein tyrosine phosphatase activity. Involved in integrin-mediated signaling pathway; modulation of chemical synaptic transmission; and regulation of focal adhesion assembly. Acts upstream of or within insulin receptor signaling pathway. Located in focal adhesion and membrane. Is active in Schaffer collateral - CA1 synapse and synaptic membrane. Is expressed in several structures, including adrenal gland; central nervous system; extraembryonic component; future brain; and genitourinary system. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LCA-related phosphatase; MGC118095; P; protein-tyrosine phosphatase alpha; PT; PTP; Ptpa; Ptpalpha; PTPTY-28; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha; RP; Rptpalpha; Rptra; Rptralpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,292,198 - 130,396,220 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,292,198 - 130,398,044 (+)EnsemblGRCm39 Ensembl
GRCm382130,450,278 - 130,554,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,450,278 - 130,556,124 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,276,014 - 130,380,036 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,194,915 - 130,245,464 (+)NCBIMGSCv36mm8
Celera2131,674,730 - 131,778,720 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. The mahogany protein is a receptor involved in suppression of obesity. Nagle DL, etal., Nature 1999 Mar 11;398(6723):148-52.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene. Pan MG, etal., J Biol Chem 1993 Sep 15;268(26):19284-91.
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Protein tyrosine-phosphatase expression profiling in gastric cancer tissues. Wu CW, etal., Cancer Lett. 2006 Oct 8;242(1):95-103. doi: 10.1016/j.canlet.2005.10.046. Epub 2005 Dec 7.
Additional References at PubMed
PMID:1454056   PMID:1590786   PMID:1686838   PMID:1932742   PMID:2162042   PMID:2166945   PMID:2169617   PMID:2170109   PMID:7518772   PMID:7537734   PMID:7832766   PMID:8075500  
PMID:8406469   PMID:8617512   PMID:8700232   PMID:8759740   PMID:8790445   PMID:8875997   PMID:8887319   PMID:8889548   PMID:9748473   PMID:10339427   PMID:10339428   PMID:10349636  
PMID:10562275   PMID:10725249   PMID:10777529   PMID:10913175   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11471062   PMID:11923305   PMID:12364328   PMID:12376545   PMID:12477932  
PMID:12582170   PMID:12598528   PMID:12826681   PMID:12834342   PMID:12912911   PMID:12932834   PMID:12952889   PMID:14610273   PMID:14733908   PMID:15623578   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16339530   PMID:16814111   PMID:16870705   PMID:16899073   PMID:17223692   PMID:17500057   PMID:17507376   PMID:17940065   PMID:18046458   PMID:18559949   PMID:18725415  
PMID:18768480   PMID:18799693   PMID:18809727   PMID:18948260   PMID:19420001   PMID:19497848   PMID:19727691   PMID:19812040   PMID:20055753   PMID:20158519   PMID:20385765   PMID:20472558  
PMID:20505149   PMID:20545765   PMID:20944008   PMID:21459125   PMID:21622556   PMID:21873635   PMID:21947380   PMID:22353164   PMID:22354965   PMID:22801373   PMID:23318421   PMID:23382219  
PMID:23452850   PMID:23934023   PMID:23940616   PMID:24005290   PMID:24248601   PMID:24650563   PMID:24694598   PMID:24821720   PMID:25826454   PMID:25951993   PMID:26414708   PMID:26590968  
PMID:28647856   PMID:29991512   PMID:30394599   PMID:30615487   PMID:31875546   PMID:32325033   PMID:32491951   PMID:34244516   PMID:35670474   PMID:36300783   PMID:37402225   PMID:38187761  


Genomics

Comparative Map Data
Ptpra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,292,198 - 130,396,220 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,292,198 - 130,398,044 (+)EnsemblGRCm39 Ensembl
GRCm382130,450,278 - 130,554,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,450,278 - 130,556,124 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,276,014 - 130,380,036 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,194,915 - 130,245,464 (+)NCBIMGSCv36mm8
Celera2131,674,730 - 131,778,720 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.23NCBI
PTPRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38202,864,184 - 3,038,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl202,873,420 - 3,039,076 (+)EnsemblGRCh38hg38GRCh38
GRCh37202,844,830 - 3,019,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,792,841 - 2,967,315 (+)NCBINCBI36Build 36hg18NCBI36
Build 34202,851,852 - 2,967,314NCBI
Celera202,907,196 - 3,081,302 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,793,748 - 2,965,653 (+)NCBIHuRef
CHM1_1202,844,843 - 3,014,144 (+)NCBICHM1_1
T2T-CHM13v2.0202,895,030 - 3,069,415 (+)NCBIT2T-CHM13v2.0
Ptpra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,103,261 - 138,212,835 (+)NCBIGRCr8
mRatBN7.23117,650,146 - 117,759,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,650,183 - 117,759,728 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,547,451 - 121,654,208 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,143,111 - 130,251,468 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,803,579 - 127,910,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,976,066 - 123,084,585 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,976,104 - 123,084,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,475,237 - 129,582,992 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,061,713 - 118,171,300 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,022,615 - 118,077,164 (+)NCBI
Celera3116,464,194 - 116,570,590 (+)NCBICelera
Cytogenetic Map3q36NCBI
Ptpra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,819,717 - 13,967,068 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,819,934 - 13,967,068 (+)NCBIChiLan1.0ChiLan1.0
PTPRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,843,586 - 4,005,991 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,840,405 - 4,002,816 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,962,701 - 3,125,282 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,726,657 - 2,888,195 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,801,905 - 2,888,195 (+)Ensemblpanpan1.1panPan2
PTPRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,224,355 - 18,395,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,224,801 - 18,296,350 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,052,684 - 18,223,899 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,643,403 - 18,815,534 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,643,403 - 18,815,666 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,236,577 - 18,408,752 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,349,051 - 18,519,508 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,677,051 - 18,848,067 (-)NCBIUU_Cfam_GSD_1.0
Ptpra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,313,690 - 167,441,022 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,744,205 - 15,872,995 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,745,054 - 15,872,377 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,637,932 - 32,797,104 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,638,494 - 32,797,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,008,987 - 37,167,722 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,559,634 - 33,724,446 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,559,697 - 33,722,137 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,789,232 - 10,956,158 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,075,101 - 4,155,130 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,997,853 - 4,155,130 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpra
3485 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:459
Count of miRNA genes:179
Interacting mature miRNAs:198
Transcripts:ENSMUST00000028769, ENSMUST00000077303
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse

Markers in Region
D2Mit78  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382130,449,734 - 130,449,948UniSTSGRCm38
MGSCv372130,275,470 - 130,275,684UniSTSGRCm37
Celera2131,674,184 - 131,674,400UniSTS
Cytogenetic Map2GUniSTS
cM Map273.5UniSTS
Whitehead Genetic260.1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF332081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF332082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ431367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL731707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY902328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX890605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028769   ⟹   ENSMUSP00000028769
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,292,198 - 130,398,044 (+)Ensembl
GRCm38.p6 Ensembl2130,450,278 - 130,556,124 (+)Ensembl
RefSeq Acc Id: ENSMUST00000077303   ⟹   ENSMUSP00000076533
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,292,464 - 130,395,943 (+)Ensembl
GRCm38.p6 Ensembl2130,450,544 - 130,554,023 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,383,545 - 130,384,424 (+)Ensembl
GRCm38.p6 Ensembl2130,541,625 - 130,542,504 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,382,257 - 130,382,939 (+)Ensembl
GRCm38.p6 Ensembl2130,540,337 - 130,541,019 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230491
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,374,591 - 130,377,544 (+)Ensembl
GRCm38.p6 Ensembl2130,532,671 - 130,535,624 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230516
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,373,890 - 130,375,303 (+)Ensembl
GRCm38.p6 Ensembl2130,531,970 - 130,533,383 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230615
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,375,050 - 130,377,970 (+)Ensembl
GRCm38.p6 Ensembl2130,533,130 - 130,536,050 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,382,403 - 130,387,232 (+)Ensembl
GRCm38.p6 Ensembl2130,540,483 - 130,545,312 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230886
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,386,453 - 130,387,344 (+)Ensembl
GRCm38.p6 Ensembl2130,544,533 - 130,545,424 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230981   ⟹   ENSMUSP00000155099
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,292,222 - 130,381,636 (+)Ensembl
GRCm38.p6 Ensembl2130,450,302 - 130,539,716 (+)Ensembl
RefSeq Acc Id: NM_001163688   ⟹   NP_001157160
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,292,198 - 130,396,220 (+)NCBI
GRCm382130,450,278 - 130,554,300 (+)NCBI
MGSCv372130,276,014 - 130,380,036 (+)RGD
Celera2131,674,730 - 131,778,720 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001355161   ⟹   NP_001342090
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,292,198 - 130,396,220 (+)NCBI
GRCm382130,450,278 - 130,554,300 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008980   ⟹   NP_033006
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,292,198 - 130,396,220 (+)NCBI
GRCm382130,450,278 - 130,554,300 (+)NCBI
MGSCv372130,276,014 - 130,380,036 (+)RGD
Celera2131,674,730 - 131,778,720 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036159699   ⟹   XP_036015592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,292,202 - 130,395,941 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033006   ⟸   NM_008980
- Peptide Label: isoform 1 precursor
- UniProtKB: A2AHF2 (UniProtKB/Swiss-Prot),   Q61808 (UniProtKB/Swiss-Prot),   P18052 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157160   ⟸   NM_001163688
- Peptide Label: isoform 2 precursor
- UniProtKB: Q91V35 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001342090   ⟸   NM_001355161
- Peptide Label: isoform 3 precursor
RefSeq Acc Id: ENSMUSP00000155099   ⟸   ENSMUST00000230981
RefSeq Acc Id: ENSMUSP00000028769   ⟸   ENSMUST00000028769
RefSeq Acc Id: ENSMUSP00000076533   ⟸   ENSMUST00000077303
RefSeq Acc Id: XP_036015592   ⟸   XM_036159699
- Peptide Label: isoform X1
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18052-F1-model_v2 AlphaFold P18052 1-829 view protein structure

Promoters
RGD ID:6847683
Promoter ID:MM_ACW:29763
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:PTPRA.DSEP07,   PTPRA.ISEP07-UNSPLICED,   PTPRA.KSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362130,366,011 - 130,366,511 (+)MPROMDB
RGD ID:6878754
Promoter ID:EPDNEW_M2828
Type:initiation region
Name:Ptpra_1
Description:Mus musculus protein tyrosine phosphatase, receptor type, A ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382130,450,282 - 130,450,342EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97808 AgrOrtholog
Ensembl Genes ENSMUSG00000027303 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028769 ENTREZGENE
  ENSMUST00000028769.14 UniProtKB/TrEMBL
  ENSMUST00000077303 ENTREZGENE
  ENSMUST00000077303.4 UniProtKB/Swiss-Prot
  ENSMUST00000230981.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_a/e-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19262 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97808 ENTREZGENE
NCBI Gene 19262 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  PTHR19134:SF433 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptpra PhenoGen
PIRSF PTPR_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPR_alpha_epsilon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHH6_MOUSE UniProtKB/TrEMBL
  A2AHF2 ENTREZGENE
  P18052 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TRY9_MOUSE UniProtKB/TrEMBL
  Q61808 ENTREZGENE
  Q91V35 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A2AHF2 UniProtKB/Swiss-Prot
  Q61808 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-16 Ptpra  protein tyrosine phosphatase receptor type A  Ptpra  protein tyrosine phosphatase, receptor type, A  Symbol and/or name change 5135510 APPROVED