Gene: Pdgfb (platelet derived growth factor, B polypeptide)  Mus musculus

Symbol: Pdgfb
Name: platelet derived growth factor, B polypeptide
Description: ENCODES a protein that exhibits cell surface binding (ortholog); chemoattractant activity (ortholog); collagen binding (ortholog); INVOLVED IN actin cytoskeleton organization; blood vessel morphogenesis; branching involved in salivary gland morphogenesis; PARTICIPATES IN platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; transforming growth factor-beta signaling pathway; ASSOCIATED WITH abnormal aorta smooth muscle morphology; abnormal artery morphology; abnormal astrocyte morphology; ASSOCIATED WITH Asthma; Diabetes Mellitus, Experimental; Fibrosis; FOUND IN basolateral plasma membrane (ortholog); cell surface (ortholog); cytoplasm (ortholog); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxynon-2-enal
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-sis; PDGF subunit B; PDGF-2; PDGF-B; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; platelet-derived growth factor subunit B; proto-oncogene c-Sis; Sis
Orthologs: Homo sapiens : PDGFB (platelet-derived growth factor beta polypeptide)  HGNC
Rattus norvegicus : Pdgfb (platelet-derived growth factor beta polypeptide)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381579,995,874 - 80,014,808-NCBI
Mouse cM Map1537.85 NCBI
Mouse Celera Assembly1582,118,153 - 82,136,874-NCBI
Mouse Genome Assembly Build 371579,826,304 - 79,845,238-NCBI
Mouse Genome Assembly Build 36.11579,826,304 - 79,845,238-NCBI
Mouse Cytogenetic Map15 E NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdgfb
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RGD Object Information
RGD ID: 11068
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2013-02-27
Status: ACTIVE