Ghrhr (growth hormone releasing hormone receptor) - Rat Genome Database

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Gene: Ghrhr (growth hormone releasing hormone receptor) Mus musculus
Analyze
Symbol: Ghrhr
Name: growth hormone releasing hormone receptor
RGD ID: 10645
MGI Page MGI
Description: Enables growth hormone-releasing hormone receptor activity and peptide hormone binding activity. Involved in positive regulation of cell population proliferation. Acts upstream of or within several processes, including determination of adult lifespan; positive regulation of growth hormone secretion; and regulation of signal transduction. Located in plasma membrane. Is expressed in alimentary system; brain; metanephros; and spinal cord. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency and isolated growth hormone deficiency type IB. Orthologous to human GHRHR (growth hormone releasing hormone receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ghr; Ghrfr; GHRH receptor; GRF receptor; GRFR; growth hormone-releasing factor receptor; growth hormone-releasing hormone receptor; lit; little
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39655,353,204 - 55,365,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl655,353,280 - 55,365,515 (+)EnsemblGRCm39 Ensembl
GRCm38655,376,295 - 55,388,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl655,376,295 - 55,388,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv37655,326,289 - 55,338,524 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36655,305,940 - 55,317,897 (+)NCBIMGSCv36mm8
Celera655,910,067 - 55,922,286 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory brainstem response  (IEA)
abnormal bone mineral density  (IEA)
abnormal bone structure  (IEA)
abnormal eating behavior  (IAGP)
abnormal frequency of paradoxical sleep  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal insulin-like growth factor I level  (IEA)
abnormal lactation  (IAGP)
abnormal metabolism  (IAGP)
abnormal postnatal growth  (IAGP)
abnormal skeleton development  (IAGP)
abnormal sleep behavior  (IEA)
abnormal sleep pattern  (IAGP)
abnormal somatotroph morphology  (IAGP)
absent somatotroph secretory granules  (IAGP)
decreased body length  (IEA)
decreased body weight  (IAGP)
decreased bone mass  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IAGP)
decreased bone mineral density of femur  (IEA)
decreased circulating glucose level  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased diameter of femur  (IAGP)
decreased diameter of tibia  (IAGP)
decreased growth hormone level  (IAGP)
decreased heart weight  (IEA)
decreased lean body mass  (IAGP)
decreased mean corpuscular hemoglobin  (IEA)
decreased prolactin level  (IAGP)
decreased somatotroph cell number  (IAGP)
decreased somatotroph cell size  (IAGP)
decreased somatotroph secretory granule number  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased vertical activity  (IEA)
decreased volumetric bone mineral density  (IEA)
hyperactivity  (IEA)
impaired glucose tolerance  (IAGP)
increased bone mineral density  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating triglyceride level  (IEA)
increased grip strength  (IEA)
increased susceptibility to age related obesity  (IAGP)
increased total body fat amount  (IAGP)
increased volumetric bone mineral density  (IAGP)
insulin resistance  (IAGP)
obese  (IAGP)
postnatal growth retardation  (IAGP)
proportional dwarf  (IAGP)
reduced male fertility  (IAGP)
short femur  (IAGP)
slow postnatal weight gain  (IAGP)
small pituitary gland  (IAGP)
thrombocytopenia  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Effects of a high-glucose environment on the pituitary growth hormone-releasing hormone receptor: type 1 diabetes compared with in vitro glucotoxicity. Bedard K, etal., Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E740-51. doi: 10.1152/ajpendo.00141.2007. Epub 2008 Feb 19.
2. Isolated GH deficiency due to a GHRH receptor mutation causes hip joint problems and genu valgum, and reduces size but not density of trabecular and mixed bone. Epitacio-Pereira CC, etal., J Clin Endocrinol Metab. 2013 Nov;98(11):E1710-5. doi: 10.1210/jc.2013-2349. Epub 2013 Sep 20.
3. Sleep loss alters hypothalamic growth hormone-releasing hormone receptors in rats. Gardi J, etal., Neurosci Lett 2002 Aug 23;329(1):69-72.
4. A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model. Majeed N, etal., Oncogene. 2005 Jul 7;24(29):4736-40.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Role of growth hormone-releasing hormone in sleep and growth impairments induced by upper airway obstruction in rats. Tarasiuk A, etal., Eur Respir J. 2011 Oct;38(4):870-7. Epub 2011 Mar 15.
15. Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse. Wajnrajch MP, etal., Nat Genet. 1996 Jan;12(1):88-90.
16. Functional GHRH receptor carboxyl terminal isoforms in normal and dwarf (dw) rats. Zeitler P, etal., J Mol Endocrinol. 1998 Dec;21(3):363-71.
Additional References at PubMed
PMID:978118   PMID:1270792   PMID:1329576   PMID:1334535   PMID:1504465   PMID:1778592   PMID:2481813   PMID:2980124   PMID:3008329   PMID:6116352   PMID:6194978   PMID:6303755  
PMID:6393185   PMID:7069343   PMID:7390396   PMID:7510770   PMID:7595148   PMID:7679139   PMID:7772239   PMID:7910409   PMID:8268652   PMID:8339285   PMID:8391647   PMID:8395283  
PMID:8504012   PMID:8618801   PMID:8661743   PMID:8680796   PMID:8769367   PMID:8827514   PMID:8887166   PMID:9300691   PMID:9457688   PMID:9802338   PMID:10349636   PMID:10459853  
PMID:10510245   PMID:10521563   PMID:10537133   PMID:10689811   PMID:10746641   PMID:10765562   PMID:10900161   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11371619   PMID:11698349  
PMID:11773624   PMID:12388430   PMID:12417729   PMID:12477932   PMID:12537301   PMID:12867592   PMID:12933669   PMID:12960295   PMID:14698815   PMID:14698816   PMID:14726438   PMID:15056934  
PMID:15059953   PMID:15165994   PMID:15308683   PMID:15363417   PMID:15388648   PMID:15644570   PMID:15690087   PMID:15963853   PMID:16141072   PMID:16141073   PMID:16355279   PMID:16384867  
PMID:16513828   PMID:16602821   PMID:16820890   PMID:17015435   PMID:17363744   PMID:17392792   PMID:17521389   PMID:17605631   PMID:18063435   PMID:18276757   PMID:18618017   PMID:19007875  
PMID:19094181   PMID:19821771   PMID:20823455   PMID:21364286   PMID:21873635   PMID:22653878   PMID:23172628   PMID:24109593   PMID:24151243   PMID:24194600   PMID:24838184   PMID:25404316  
PMID:26134413   PMID:26219867   PMID:26828925   PMID:27626380   PMID:27631552   PMID:28700664   PMID:31436800   PMID:32229232   PMID:33888610   PMID:34971379   PMID:37030549   PMID:37616545  


Genomics

Comparative Map Data
Ghrhr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39655,353,204 - 55,365,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl655,353,280 - 55,365,515 (+)EnsemblGRCm39 Ensembl
GRCm38655,376,295 - 55,388,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl655,376,295 - 55,388,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv37655,326,289 - 55,338,524 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36655,305,940 - 55,317,897 (+)NCBIMGSCv36mm8
Celera655,910,067 - 55,922,286 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
GHRHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,963,953 - 30,979,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,938,669 - 30,993,254 (+)EnsemblGRCh38hg38GRCh38
GRCh37731,003,568 - 31,019,143 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,970,161 - 30,985,668 (+)NCBINCBI36Build 36hg18NCBI36
Build 34730,776,875 - 30,788,828NCBI
Celera730,992,840 - 31,008,351 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,885,854 - 30,901,378 (+)NCBIHuRef
CHM1_1731,003,564 - 31,019,092 (+)NCBICHM1_1
T2T-CHM13v2.0731,101,596 - 31,117,172 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2731,053,140 - 31,068,651 (+)NCBI
Ghrhr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,830,345 - 85,863,127 (+)NCBIGRCr8
mRatBN7.2484,498,159 - 84,532,851 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl484,500,212 - 84,532,776 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,718,589 - 89,754,998 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0485,493,999 - 85,530,402 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,899,789 - 83,936,121 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,587,321 - 85,602,389 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,588,595 - 85,601,666 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04150,221,064 - 150,253,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4484,135,530 - 84,148,503 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1484,421,996 - 84,434,974 (+)NCBI
Celera479,386,911 - 79,400,313 (+)NCBICelera
Cytogenetic Map4q24NCBI
Ghrhr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,102,367 - 32,115,080 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541032,084,210 - 32,114,844 (+)NCBIChiLan1.0ChiLan1.0
GHRHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2635,775,238 - 35,790,875 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1784,099,966 - 84,115,603 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0731,582,134 - 31,592,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1731,701,641 - 31,712,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl731,696,914 - 31,712,200 (+)Ensemblpanpan1.1panPan2
GHRHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11443,626,862 - 43,638,737 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1443,626,845 - 43,638,753 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1443,059,230 - 43,070,721 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01443,567,602 - 43,579,114 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1443,567,473 - 43,579,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11443,683,226 - 43,694,708 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01443,359,784 - 43,371,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01443,721,032 - 43,732,545 (+)NCBIUU_Cfam_GSD_1.0
Ghrhr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511887,980,695 - 87,991,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364787,188,826 - 7,201,932 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364787,188,826 - 7,202,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHRHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,030,510 - 42,046,184 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11842,030,505 - 42,046,178 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21846,427,131 - 46,436,821 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHRHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12127,402,765 - 27,417,536 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2127,404,886 - 27,417,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604277,286,895 - 77,301,754 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ghrhr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624783200,940 - 214,373 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624783200,935 - 214,453 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ghrhr
403 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:180
Count of miRNA genes:162
Interacting mature miRNAs:169
Transcripts:ENSMUST00000063578
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
14696807Rbcn2_mrod bipolar cell number 2 (mouse)65118698056186985Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse

Markers in Region
Ghrhr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6B3UniSTS
cM Map626.0UniSTS
Ghrhr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38655,378,878 - 55,379,192UniSTSGRCm38
MGSCv37655,328,872 - 55,329,186UniSTSGRCm37
Celera655,912,626 - 55,912,940UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000063578   ⟹   ENSMUSP00000068120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl655,353,328 - 55,365,515 (+)Ensembl
GRCm38.p6 Ensembl655,376,343 - 55,388,530 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203241   ⟹   ENSMUSP00000145224
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl655,353,350 - 55,365,304 (+)Ensembl
GRCm38.p6 Ensembl655,376,365 - 55,388,319 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl655,353,280 - 55,359,845 (+)Ensembl
GRCm38.p6 Ensembl655,376,295 - 55,382,860 (+)Ensembl
RefSeq Acc Id: NM_001003685   ⟹   NP_001003685
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39655,353,280 - 55,365,515 (+)NCBI
GRCm38655,376,295 - 55,388,530 (+)NCBI
MGSCv37655,326,289 - 55,338,524 (+)RGD
Celera655,910,067 - 55,922,286 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036165843   ⟹   XP_036021736
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39655,353,204 - 55,362,372 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003685 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021736 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI20749 (Get FASTA)   NCBI Sequence Viewer  
  AAI20775 (Get FASTA)   NCBI Sequence Viewer  
  EDK98729 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000068120
  ENSMUSP00000068120.4
  ENSMUSP00000145224.2
GenBank Protein P32082 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001003685   ⟸   NM_001003685
- Peptide Label: precursor
- UniProtKB: Q0VB62 (UniProtKB/Swiss-Prot),   P32082 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000145224   ⟸   ENSMUST00000203241
RefSeq Acc Id: ENSMUSP00000068120   ⟸   ENSMUST00000063578
RefSeq Acc Id: XP_036021736   ⟸   XM_036165843
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 2 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P32082-F1-model_v2 AlphaFold P32082 1-423 view protein structure

Promoters
RGD ID:6889808
Promoter ID:EPDNEW_M8355
Type:initiation region
Name:Ghrhr_1
Description:Mus musculus growth hormone releasing hormone receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38655,376,342 - 55,376,402EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95710 AgrOrtholog
Ensembl Genes ENSMUSG00000004654 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000063578 ENTREZGENE
  ENSMUST00000063578.6 UniProtKB/Swiss-Prot
  ENSMUST00000203241.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_GHRH_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14602 UniProtKB/Swiss-Prot
MGD MGI:95710 ENTREZGENE
NCBI Gene 14602 ENTREZGENE
PANTHER PDF RECEPTOR-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45620:SF14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ghrhr PhenoGen
PRINTS GHRHRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HormR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
  SSF111418 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SVS4_MOUSE UniProtKB/TrEMBL
  GHRHR_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q0VB62 ENTREZGENE
UniProt Secondary Q0VB62 UniProtKB/Swiss-Prot