Gene: Cast (calpastatin)  Mus musculus

Symbol: Cast
Name: calpastatin
Description: ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN negative regulation of peptidase activity; cell cycle (ortholog); egg activation (ortholog); PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; ASSOCIATED WITH abnormal survival; complete embryonic lethality during organogenesis; hemorrhage; ASSOCIATED WITH Alzheimer Disease; Malaria, Cerebral; Phenylketonurias; FOUND IN membrane; cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH cisplatin; cyclosporin A; microcystin-LR
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calpain inhibitor; calpastatin; calpastatin type III
Orthologs: Homo sapiens : CAST (calpastatin)  HGNC
Rattus norvegicus : Cast (calpastatin)
Related Pseudogenes: Gm6386   Gm8184  
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381374,694,286 - 74,807,921-NCBI
Mouse cM Map13 -NCBI
Mouse Celera Assembly1377,024,381 - 77,127,605-NCBI
Mouse Genome Assembly Build 371374,831,734 - 74,945,369-NCBI
Mouse Genome Assembly Build 36.11374,831,734 - 74,945,369-NCBI
Mouse Cytogenetic Map13 C1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cast
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 10292
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2013-02-27
Status: ACTIVE