Adrb2 (adrenergic receptor, beta 2)

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Keyword

Gene: Adrb2 (adrenergic receptor, beta 2) Mus musculus

Symbol:

Adrb2

Name:

adrenergic receptor, beta 2

Description:

This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. The encoded protein is a beta-2 adrenergic receptor which is activated by catecholamine ligands such as adrenaline and epinephrine. The protein participates in the classical signaling pathway involving G protein, adenylyl cyclase, cAMP (3'-5'-cyclic adenosine monophosphate) and protein kinase A (PKA). In humans, this gene is implicated in susceptibility to nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Apr 2013]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

Adrb-2; Badm; beta 2-adrenoceptor; beta 2-AR; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; Gpcr7

Orthologs:

Homo sapiens : ADRB2 (adrenoceptor beta 2, surface) HGNC
Rattus norvegicus : Adrb2 (adrenoceptor beta 2, surface)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	18	62,177,816 - 62,179,959	-	NCBI
Mouse cM Map	18	35.1		NCBI
Mouse Celera Assembly	18	63,462,804 - 63,464,949	-	NCBI
Mouse Genome Assembly Build 37	18	62,337,470 - 62,339,613	-	NCBI
Mouse Genome Assembly Build 36.1	18	62,337,470 - 62,339,613	-	NCBI
Mouse Cytogenetic Map	18	E1		NCBI