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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311472 Species: Rattus norvegicus RGD Object: Gene Symbol: Spry2 Name: sprouty homolog 2 (Drosophila)

Acc ID: CHEBI:9927 Term: valsartan Definition: A biphenylyltetrazole that has formula C24H29N5O3. CasRN: 137862-53-4 Chemical ID: MESH:C081489

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1322949	6480464	CTD	valsartan inhibits the reaction [AGT protein results in increased expression of SPRY2 mRNA]	PMID:19225232