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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2451
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cycs
Name: cytochrome c, somatic
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cycsaffects localizationISOCYCS (Homo sapiens)6480464CTDtroglitazone affects the localization of CYCS proteinPMID:22108328
Cycsdecreases expressionISOCYCS (Homo sapiens)6480464CTDtroglitazone results in decreased expression of CYCS mRNAPMID:20860658
Cycsincreases expressionISOCYCS (Homo sapiens)6480464CTDtroglitazone results in increased expression of CYCSPMID:12680223
Cycsmultiple interactionsISOCYCS (Homo sapiens)6480464CTD[2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [troglitazone affects the localization of CYCS protein]PMID:22108328
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