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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2195
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcat1
Name: branched chain amino acid transaminase 1
Acc ID: CHEBI:9671
Term: triamterene
Definition: Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.
Chemical ID: MESH:D014223
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcat1increases expressionEXP 6480464CTDTriamterene results in increased expression of BCAT1 mRNAPMID:23558518
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