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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2561
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Acc ID: CHEBI:9570
Term: Thiotepa
Definition: An aziridine that has formula C6H12N3PS.
Chemical ID: MESH:D013852
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Erbb2affects response to substanceISOERBB2 (Homo sapiens)6480464CTDERBB2 protein affects the susceptibility to ThiotepaPMID:10327070
Erbb2multiple interactionsISOERBB2 (Homo sapiens)6480464CTDERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin]PMID:16446318
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