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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3880
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Faslg
Name: Fas ligand
Acc ID: CHEBI:9513
Term: thalidomide
Definition: A racemate comprising equimolar amounts of R- and S-thalidomide.
Chemical ID: MESH:D013792
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Faslgdecreases expressionISOFASLG (Homo sapiens)6480464CTDThalidomide results in decreased expression of FASLG proteinPMID:16531263
Faslgmultiple interactionsISOFasl (Mus musculus)6480464CTDThalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of FASL mRNA]PMID:16510725
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