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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:94995
Term: 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Definition: A quinuclidine that has formula C9H15NO3.
Chemical ID: MESH:C451219
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTD2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased cleavage of and results in increased activity of CASP3 proteinPMID:21109480
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