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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733197
Species: Homo sapiens
RGD Object: Gene
Symbol: TRPV1
Name: transient receptor potential cation channel subfamily V member 1
Acc ID: CHEBI:9468
Term: tetracaine
Definition: A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Chemical ID: MESH:D013748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TRPV1increases activityISOTrpv1 (Rattus norvegicus)6480464CTDTetracaine results in increased activity of TRPV1 proteinPMID:18172555
TRPV1multiple interactionsISOTrpv1 (Rattus norvegicus)6480464CTDTetracaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]PMID:15854744
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