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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:9466
Term: Testosterone propionate
Definition: A steroid ester that has formula C22H32O3.
Chemical ID: MESH:D043343
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Araffects bindingEXP 6480464CTDTestosterone Propionate binds to AR proteinPMID:14565775
Arincreases expressionEXP 6480464CTDTestosterone Propionate results in increased expression of AR proteinPMID:23669243
Armultiple interactionsISOAr (Mus musculus)6480464CTDTestosterone Propionate inhibits the reaction [Endosulfan results in decreased expression of AR mRNA]PMID:25077688
Armultiple interactionsISOAR (Homo sapiens)6480464CTDTestosterone Propionate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]PMID:33049310
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