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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:94598
Term: 1-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-2-(4-chlorophenoxy)ethanone
Definition: A benzodioxole that has formula C20H21ClN2O4.
Chemical ID: MESH:C038628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDfipexide results in increased activity of CASP3 proteinPMID:22700542
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDPalmitic Acid promotes the reaction [fipexide results in increased activity of CASP3 protein]PMID:22700542
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