GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | affects activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Itraconazole affects the activity of ABCB1 protein | PMID:15964336 | Abcb1a | affects transport | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | ABCB1 protein affects the transport of Itraconazole | PMID:15905803 | Abcb1a | decreases activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Itraconazole results in decreased activity of ABCB1 protein | PMID:15905803 PMID:15969931 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Itraconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]; Itraconazole promotes the reaction [ABCB1 gene SNP affects the susceptibility to fexofenadine] | PMID:15969931 PMID:16084853 | |
Go Back to source page | Continue to Ontology report |