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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857 Species: Rattus norvegicus RGD Object: Gene Symbol: Icam1 Name: intercellular adhesion molecule 1

Acc ID: CHEBI:9434 Term: telmisartan Definition: A biphenylyltetrazole that has formula C33H30N4O2. CasRN: 144701-48-4 Chemical ID: MESH:C084178

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:69659	6480464	CTD	telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]	PMID:22124178
multiple interactions	ISO	RGD:10756	6480464	CTD	telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]	PMID:17724226
multiple interactions	EXP		6480464	CTD	telmisartan inhibits the reaction [Daunorubicin results in increased expression of ICAM1 protein]	PMID:20888384