GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 mRNA]; tangeretin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFE2L2 protein]; tangeretin inhibits the reaction [Cisplatin results in increased expression of NFE2L2 protein] | PMID:24995432 PMID:27616468 | Nfe2l2 | decreases methylation | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | tangeretin metabolite results in decreased methylation of NFE2L2 promoter; tangeretin results in decreased methylation of NFE2L2 promoter | PMID:37517432 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | tangeretin metabolite results in increased expression of NFE2L2 mRNA; tangeretin metabolite results in increased expression of NFE2L2 protein; tangeretin results in increased expression of NFE2L2 mRNA; tangeretin results in increased expression of NFE2L2 protein | PMID:37517432 | |
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