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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109 Species: Mus musculus RGD Object: Gene Symbol: Col1a1 Name: collagen, type I, alpha 1

Acc ID: CHEBI:9334 Term: sulfasalazine Definition: An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position. CasRN: 599-79-1 Chemical ID: MESH:D012460

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:61817	6480464	CTD	Sulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	PMID:15633128