GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
621316
Species:
Rattus norvegicus
RGD Object:
Gene
Symbol:
Mmp2
Name:
matrix metallopeptidase 2
Acc ID:
CHEBI:9288
Term:
streptozocin
Definition:
An antibiotic that is produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
CasRN:
18883-66-4
Chemical ID:
MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions ISO RGD:730821 6480464 CTD PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] PMID:20446767 increases expression ISO RGD:730822 6480464 CTD Streptozocin results in increased expression of MMP2 mRNA PMID:20446767 multiple interactions EXP 6480464 CTD benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA] PMID:20821936 decreases expression EXP 6480464 CTD Streptozocin results in decreased expression of MMP2 protein PMID:20821936 multiple interactions ISO RGD:730822 6480464 CTD pimagedine inhibits the reaction [Streptozocin results in increased activity of MMP2 protein] PMID:22543014 increases activity ISO RGD:730822 6480464 CTD Streptozocin results in increased activity of MMP2 protein PMID:22543014 multiple interactions EXP 6480464 CTD benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA] PMID:20821936 PMID:16732983 multiple interactions EXP 6480464 CTD benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein] PMID:16732983 PMID:20821936 decreases expression EXP 6480464 CTD Streptozocin results in decreased expression of MMP2 mRNA PMID:20821936 PMID:16732983 decreases expression EXP 6480464 CTD Streptozocin results in decreased expression of MMP2 mRNA PMID:16732983 PMID:20821936 
