GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nox4 | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of NOX4 mRNA | PMID:16979161 | Nox4 | multiple interactions | EXP | | 6480464 | CTD | [Resveratrol co-treated with Streptozocin] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA] | PMID:16979161 PMID:25905778 PMID:35085591 | Nox4 | multiple interactions | ISO | Nox4 (Mus musculus) | 6480464 | CTD | [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein] | PMID:29127188 PMID:35961541 | | ||||||||||||||||||||||
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