• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070 Species: Rattus norvegicus RGD Object: Gene Symbol: Agtr1a Name: angiotensin II receptor, type 1a

Acc ID: CHEBI:9288 Term: streptozocin Definition: An antibiotic that is produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. CasRN: 18883-66-4 Chemical ID: MESH:D013311

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:737190	6480464	CTD	Streptozocin results in increased expression of AGTR1A mRNA	PMID:17724226
multiple interactions	ISO	RGD:737190	6480464	CTD	telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]	PMID:21381899
increases expression	ISO	RGD:737190	6480464	CTD	Streptozocin results in increased expression of AGTR1A protein	PMID:21381899 PMID:18487452 PMID:17724226
increases expression	ISO	RGD:737190	6480464	CTD	Streptozocin results in increased expression of AGTR1A protein	PMID:17724226 PMID:18487452 PMID:21381899
increases expression	ISO	RGD:737190	6480464	CTD	Streptozocin results in increased expression of AGTR1A protein	PMID:18487452 PMID:21381899 PMID:17724226
increases expression	ISO	RGD:737190	6480464	CTD	Streptozocin results in increased expression of AGTR1A protein	PMID:17724226 PMID:21381899 PMID:18487452