GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agtr1a | multiple interactions | EXP | | 6480464 | CTD | [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA] | PMID:28946194 | Agtr1a | increases expression | ISO | Agtr1a (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein | PMID:17724226 PMID:18487452 PMID:21381899 PMID:29266779 PMID:30184259 | Agtr1a | multiple interactions | ISO | Agtr1a (Mus musculus) | 6480464 | CTD | 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein] | PMID:21381899 PMID:29266779 PMID:30184259 PMID:37120126 | | ||||||||||||||||||||||
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