GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | increases expression | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Spironolactone results in increased expression of ABCB1 mRNA; Spironolactone results in increased expression of ABCB1 protein | PMID:21459122 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]; NR1I2 affects the reaction [Spironolactone results in increased expression of ABCB1 protein] | PMID:21459122 | |
Go Back to source page | Continue to Ontology report |