GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nppa | multiple interactions | EXP | | 6480464 | CTD | Spironolactone inhibits the reaction [Aldosterone results in increased expression of NPPA mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Spironolactone inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] | PMID:19966502 PMID:23288202 | Nppa | decreases expression | ISO | NPPA (Homo sapiens) | 6480464 | CTD | Spironolactone results in decreased expression of NPPA protein; Spironolactone results in decreased expression of NPPA protein modified form | PMID:11300427 PMID:9595286 | |
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