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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3224
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a1
Name: solute carrier family 22 member 1
Acc ID: CHEBI:92246
Term: N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine
Definition: An aralkylamine that has formula C13H22N4O3S.
Chemical ID: MESH:D011899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a1increases uptakeEXP 6480464CTDSLC22A1 protein results in increased uptake of RanitidinePMID:16006492
Slc22a1affects transportISOSLC22A1 (Homo sapiens)6480464CTDSLC22A1 protein affects the transport of RanitidinePMID:16141367
Slc22a1multiple interactionsISOSLC22A1 (Homo sapiens)6480464CTDRanitidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]PMID:16141367 PMID:16263091
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