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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61312
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Timp2
Name: TIMP metallopeptidase inhibitor 2
Acc ID: CHEBI:9190
Term: solasodine
Definition: An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills.
Chemical ID: MESH:C012037
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Timp2increases expressionISOTIMP2 (Homo sapiens)6480464CTDsolasodine results in increased expression of TIMP2 mRNAPMID:28283413
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