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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:91583
Term: 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
Definition: An isoquinoline that has formula C19H24N2O2.
Chemical ID: MESH:D011223
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases expressionISOVegfa (Mus musculus)6480464CTDPraziquantel results in decreased expression of VEGFA mRNA; Praziquantel results in decreased expression of VEGFA proteinPMID:24818384
Vegfamultiple interactionsISOVegfa (Mus musculus)6480464CTD[Resveratrol co-treated with Praziquantel] results in decreased expression of VEGFA mRNA; [Resveratrol co-treated with Praziquantel] results in decreased expression of VEGFA proteinPMID:24818384
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