GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | App | multiple interactions | EXP | | 6480464 | CTD | Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] | PMID:28734741 | App | decreases activity | ISO | APP (Homo sapiens) | 6480464 | CTD | Simvastatin results in decreased activity of APP protein alternative form | PMID:17241114 | App | multiple interactions | ISO | APP (Homo sapiens) | 6480464 | CTD | oblimersen inhibits the reaction [Simvastatin results in decreased activity of APP protein alternative form]; Simvastatin inhibits the reaction [APP protein alternative form results in decreased expression of CASP3 protein]; Simvastatin inhibits the reaction [APP protein alternative form results in increased activity of CASP3 protein] | PMID:17241114 | | ||||||||||||||||||||||
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