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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359491
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pou5f1
Name: POU class 5 homeobox 1
Acc ID: CHEBI:91462
Term: SU6656
Definition: A member of the class of oxindoles that is 3-methyleneoxindole in which the hydrogeh at position 5 has been replaced by a dimethylaminosulfonyl group and in which one of the hydrogens of the methylene group has been replaced by a 4,5,6,7-tetrahydro-indol-2-yl group. It is a specific inhibitor of Src family kinase.
Chemical ID: MESH:C416927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pou5f1decreases expressionISOPOU5F1 (Homo sapiens)6480464CTDSU 6656 results in decreased expression of POU5F1 proteinPMID:23527294
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