GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | SB 203580 inhibits the reaction [Doxorubicin results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Doxorubicin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [gadolinium chloride results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Lipopolysaccharides results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 promotes the reaction [U 0126 inhibits the reaction [Lipopolysaccharides results in increased activity of MMP9 protein]]; U 0126 promotes the reaction [SB 203580 inhibits the reaction [Lipopolysaccharides results in increased activity of MMP9 protein]] | PMID:12493575 PMID:16213474 PMID:16683234 PMID:29079362 | Mmp9 | decreases activity | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | SB 203580 results in decreased activity of MMP9 protein | PMID:22033475 | Mmp9 | decreases activity | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | SB 203580 results in decreased activity of MMP9 protein | PMID:15657063 | Mmp9 | decreases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | SB 203580 results in decreased expression of MMP9 mRNA; SB 203580 results in decreased expression of MMP9 protein | PMID:27829220 PMID:30801954 | Mmp9 | decreases expression | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | SB 203580 results in decreased expression of MMP9 mRNA | PMID:15657063 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | [kahweol acetate co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; SB 203580 inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP9 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP9 protein]]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Oxidopamine results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [taiwanin E results in decreased expression of MMP9 protein]; SB 203580 inhibits the reaction [tetrabromobisphenol A results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [thymoquinone results in decreased expression of MMP9 protein]; SB 203580 inhibits the reaction [TNF protein results in increased expression of and results in increased activity of MMP9 protein]; SB 203580 promotes the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; SB 203580 promotes the reaction [ovatodiolide results in decreased activity of MMP9 protein]; SB 203580 promotes the reaction [Resveratrol results in decreased expression of MMP9]; SB 203580 promotes the reaction [Resveratrol results in increased expression of and results in increased activity of MMP9 protein] | PMID:15728660 PMID:19962414 PMID:20152819 PMID:21354279 PMID:22033475 PMID:22705379 PMID:23229870 PMID:24841706 PMID:25200491 PMID:26179980 PMID:26807887 PMID:27060453 PMID:27807932 PMID:27829220 PMID:30590137 PMID:30766661 PMID:36413041 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | SB 203580 inhibits the reaction [Leukotriene B4 results in increased expression of MMP9 protein]; SB 203580 inhibits the reaction [Leukotriene C4 results in increased expression of MMP9 protein]; SB 203580 inhibits the reaction [Leukotriene D4 results in increased expression of MMP9 protein]; SB 203580 inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MMP9 protein] | PMID:19837106 PMID:27818224 | | ||||||||||||||||||||||
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