GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | App | multiple interactions | ISO | APP (Homo sapiens) | 6480464 | CTD | SB 203580 inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; SB 203580 inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; SB 203580 inhibits the reaction [APP protein results in increased expression of NLRP3 protein]; SB 203580 inhibits the reaction [Copper results in increased expression of APP mRNA] | PMID:18583042 PMID:28004443 | |
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