GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | multiple interactions | EXP | | 6480464 | CTD | SB 203580 inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]]; SB 203580 inhibits the reaction [AGT protein modified form results in increased activity of GATA4 protein]; SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of FGF2 mRNA]; SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of FGF2 protein]; SB 203580 inhibits the reaction [AGT protein results in increased expression of POSTN mRNA]; SB 203580 inhibits the reaction [AGT protein results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [AGT protein results in increased expression of REG3G mRNA]; SB 203580 inhibits the reaction [AGT protein results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT protein] | PMID:12130563 PMID:17485602 PMID:19145780 PMID:21108934 PMID:23300732 PMID:27798352 | Agt | decreases response to substance | ISO | Agt (Mus musculus) | 6480464 | CTD | SB 203580 results in decreased susceptibility to AGT protein modified form | PMID:21289285 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | SB 203580 inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]; SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of ARG1 protein]; SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of ARG2 protein] | PMID:21289285 | | ||||||||||||||||||||||
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