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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cftr
Name: CF transmembrane conductance regulator
Acc ID: CHEBI:9012
Term: Salmeterol xinafoate
Definition: null
Chemical ID: MESH:D000068299
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cftrincreases expressionISOCFTR (Homo sapiens)6480464CTDSalmeterol Xinafoate results in increased expression of CFTR proteinPMID:12621035
Cftrmultiple interactionsISOCFTR (Homo sapiens)6480464CTD[Salmeterol Xinafoate binds to ADRB2 protein] which results in increased expression of CFTR protein; Salmeterol Xinafoate promotes the reaction [CFTR protein binds to NHERF1 protein]PMID:12621035
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