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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2061
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adrb3
Name: adrenoceptor beta 3
Acc ID: CHEBI:9012
Term: Salmeterol xinafoate
Definition: null
Chemical ID: MESH:D000068299
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adrb3multiple interactionsISOADRB3 (Homo sapiens)6480464CTD[Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein; Salmeterol Xinafoate inhibits the reaction [cyanopindolol binds to ADRB3 protein]PMID:14730417
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