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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731357 Species: Mus musculus RGD Object: Gene Symbol: Akap1 Name: A kinase (PRKA) anchor protein 1

Acc ID: CHEBI:8772 Term: raloxifene Definition: A benzothiophene that has formula C28H27NO4S. CasRN: 84449-90-1 Chemical ID: MESH:D020849

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:1343676	6480464	CTD	Raloxifene affects the expression of AKAP1 mRNA	PMID:14699072
multiple interactions	ISO	RGD:1343676	6480464	CTD	[Raloxifene co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA	PMID:19059307