GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp7 | multiple interactions | ISO | CASP7 (Homo sapiens) | 6480464 | CTD | palbociclib inhibits the reaction [Camptothecin results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Carboplatin results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Paclitaxel results in increased activity of CASP7 protein] | PMID:22302033 | Casp7 | multiple interactions | ISO | Casp7 (Mus musculus) | 6480464 | CTD | [CDKN2A gene mutant form results in increased susceptibility to palbociclib] which affects the activity of CASP7 protein | PMID:24098593 | |
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