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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736217 Species: Homo sapiens RGD Object: Gene Symbol: CYP2D6 Name: cytochrome P450, family 2, subfamily D, polypeptide 6

Acc ID: CHEBI:8502 Term: 6-propyl-2-thiouracil Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group. CasRN: 51-52-5 Chemical ID: MESH:D011441

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:620640	6480464	CTD	Propylthiouracil affects the expression of CYP2D4 mRNA	PMID:19483382
affects expression	ISO	RGD:2472	6480464	CTD	Propylthiouracil affects the expression of CYP2D3 mRNA	PMID:19483382