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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379 Species: Rattus norvegicus RGD Object: Gene Symbol: Cyp3a2 Name: cytochrome P450, family 3, subfamily a, polypeptide 2

Acc ID: CHEBI:8489 Term: propiconazole Definition: The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a racemic mixture of diastereoisomers on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds. CasRN: 60207-90-1 Chemical ID: MESH:C045950

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	propiconazole results in increased expression of CYP3A2 mRNA	PMID:15603923