GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a2 | affects metabolic processing | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | CYP1A2 protein affects the metabolism of Primaquine | PMID:12920490 | Cyp1a2 | increases activity | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | Primaquine results in increased activity of CYP1A2 promoter | PMID:18502397 | Cyp1a2 | increases expression | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | Primaquine results in increased expression of CYP1A2 mRNA | PMID:12451431 PMID:12623754 PMID:17954527 | Cyp1a2 | increases metabolic processing | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | CYP1A2 protein results in increased metabolism of Primaquine | PMID:19616568 | Cyp1a2 | multiple interactions | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | [CYP1A2 protein results in increased expression of HBG2 protein] which affects the susceptibility to Primaquine | PMID:19616568 | |
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