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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962 Species: Homo sapiens RGD Object: Gene Symbol: CYP3A4 Name: cytochrome P450, family 3, subfamily A, polypeptide 4

Acc ID: CHEBI:8378 Term: prednisolone Definition: A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. CasRN: 50-24-8 Chemical ID: MESH:D011239

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	Prednisolone results in increased expression of CYP3A4 mRNA	PMID:12673034