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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620461
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nphs2
Name: NPHS2 stomatin family member, podocin
Acc ID: CHEBI:83267
Term: filipin III
Definition: A macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis.
Chemical ID: MESH:D005372
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nphs2multiple interactionsISONphs2 (Mus musculus)6480464CTDFilipin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; Filipin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]PMID:20036696
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