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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:82664
Term: iron(0)
Definition: An elemental iron in which the atom has an oxidation state of zero.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasaffects localizationEXP 6480464CTDIron affects the localization of HRAS proteinPMID:17172471
Hrasmultiple interactionsEXP 6480464CTDHRAS protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK3 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; Iron promotes the reaction [MAP3K7 protein binds to HRAS protein binds to PIK3R1 protein]PMID:17172471
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