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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620404
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adam17
Name: ADAM metallopeptidase domain 17
Acc ID: CHEBI:82346
Term: Methylthiouracil
Definition: A pyrimidone that has formula C5H6N2OS.
Chemical ID: MESH:D008779
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adam17multiple interactionsISOADAM17 (Homo sapiens)6480464CTDMethylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ADAM17 protein]; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]PMID:26298005
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