Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2981
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Kras
Name:	KRAS proto-oncogene, GTPase

Acc ID:	CHEBI:82290
Term:	Benz[j]aceanthrylene
Definition:	A phenanthrene that has formula C20H12.
Chemical ID:	MESH:C037411

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Kras	increases mutagenesis	ISO	Kras (Mus musculus)	6480464	CTD	benz(j)aceanthrylene results in increased mutagenesis of KRAS gene	PMID:9659573

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.