GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bace1 | decreases activity | ISO | BACE1 (Homo sapiens) | 6480464 | CTD | pioglitazone results in decreased activity of BACE1 protein | PMID:14586007 | Bace1 | decreases expression | ISO | Bace1 (Mus musculus) | 6480464 | CTD | pioglitazone results in decreased expression of BACE1 mRNA; pioglitazone results in decreased expression of BACE1 protein | PMID:15817521 PMID:16407166 | Bace1 | decreases expression | ISO | BACE1 (Homo sapiens) | 6480464 | CTD | pioglitazone results in decreased expression of BACE1 mRNA | PMID:14586007 | Bace1 | multiple interactions | ISO | BACE1 (Homo sapiens) | 6480464 | CTD | pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein] | PMID:14586007 | |
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